More Like this

1. Quantification of red myotomal muscle volume and geometry in the shortfin mako shark ( Isurus oxyrinchus ) and the salmon shark ( Lamna ditropis ) using T 1 -weighted magnetic resonance imaging

   https://doi.org/10.1002/jmor.10516  

   Perry, Cameron N. ; Cartamil, Daniel P. ; Bernal, Diego ; Sepulveda, Chugey A. ; Theilmann, Rebecca J. ; Graham, Jeffrey B. ; Frank, Lawrence R. ( April 2007 , Journal of Morphology)
2. Rapid volumetric gagCEST imaging of knee articular cartilage at 3 T: evaluation of improved dynamic range and an osteoarthritic population

   https://doi.org/10.1002/nbm.4310  

   Watkins, Lauren E. ; Rubin, Elka B. ; Mazzoli, Valentina ; Uhlrich, Scott D. ; Desai, Arjun D. ; Black, Marianne ; Ho, Gabe K. ; Delp, Scott L. ; Levenston, Marc E. ; Beaupré, Gary S. ; et al ( May 2020 , NMR in Biomedicine)

   Chemical exchange saturation transfer of glycosaminoglycans, gagCEST, is a quantitative MR technique that has potential for assessing cartilage proteoglycan content at field strengths of 7 T and higher. However, its utility at 3 T remains unclear. The objective of this work was to implement a rapid volumetric gagCEST sequence with higher gagCEST asymmetry at 3 T to evaluate its sensitivity to osteoarthritic changes in knee articular cartilage and in comparison withT₂andT_1ρmeasures. We hypothesize that gagCEST asymmetry at 3 T decreases with increasing severity of osteoarthritis (OA). Forty‐two human volunteers, including 10 healthy subjects and 32 subjects with medial OA, were included in the study. Knee Injury and Osteoarthritis Outcome Scores (KOOS) were assessed for all subjects, and Kellgren‐Lawrence grading was performed for OA volunteers. Healthy subjects were scanned consecutively at 3 T to assess the repeatability of the volumetric gagCEST sequence at 3 T. For healthy and OA subjects, gagCEST asymmetry andT₂andT_1ρrelaxation times were calculated for the femoral articular cartilage to assess sensitivity to OA severity. Volumetric gagCEST imaging had higher gagCEST asymmetry than single‐slice acquisitions (p= 0.015). The average scan‐rescan coefficient of variation was 6.8%. There were no significant differences in average gagCEST asymmetry between younger and older healthy controls (p= 0.655) or between healthy controls and OA subjects (p= 0.310).T₂andT_1ρrelaxation times were elevated in OA subjects (p< 0.001 for both) compared with healthy controls and both were moderately correlated with total KOOS scores (rho = −0.181 and rho = −0.332 respectively). The gagCEST technique developed here, with volumetric scan times under 10 min and high gagCEST asymmetry at 3 T, did not vary significantly between healthy subjects and those with mild‐moderate OA. This further supports a limited utility for gagCEST imaging at 3 T for assessment of early changes in cartilage composition in OA.

    

   more » « less
3. Unexpected Trend Deviation in Isoelectronic Transition Metal Borides A 3 T 5 B 2 ( A = group 4, T = group 9): Ti 3 Co 5 B 2 - vs. Perovskite-Type Studied by Experiments and DFT Calculations: Unexpected Trend Deviation in Isoelectronic Transition Metal Borides A3T5B2 (A = group 4, T = group 9): Ti3Co5B2- vs. Perovskite-Type Studied by Exper

   https://doi.org/10.1002/zaac.201700271  

   Shankhari, Pritam ; Scheifers, Jan P. ; Hermus, Martin ; Yubuta, Kunio ; Fokwa, Boniface P. ( November 2017 , Zeitschrift für anorganische und allgemeine Chemie)
4. Free‐breathing simultaneous T 1 , T 2 , and T 2 ∗ quantification in the myocardium

   https://doi.org/10.1002/mrm.28753  

   Hermann, Ingo ; Kellman, Peter ; Demirel, Omer B. ; Akçakaya, Mehmet ; Schad, Lothar R. ; Weingärtner, Sebastian ( September 2021 , Magnetic Resonance in Medicine)
5. Imaging and T 2 relaxometry of short‐T 2 connective tissues in the knee using ultrashort echo‐time double‐echo steady‐state (UTEDESS)

   https://doi.org/10.1002/mrm.26577  

   Chaudhari, Akshay S. ; Sveinsson, Bragi ; Moran, Catherine J. ; McWalter, Emily J. ; Johnson, Ethan M. ; Zhang, Tao ; Gold, Garry E. ; Hargreaves, Brian A. ( January 2017 , Magnetic Resonance in Medicine)

   To develop a radial, double‐echo steady‐state (DESS) sequence with ultra‐short echo‐time (UTE) capabilities for T₂measurement of short‐T₂tissues along with simultaneous rapid, signal‐to‐noise ratio (SNR)‐efficient, and high‐isotropic‐resolution morphological knee imaging.

   THe 3D radial UTE readouts were incorporated into DESS, termed UTEDESS. Multiple‐echo‐time UTEDESS was used for performing T₂relaxometry for short‐T₂tendons, ligaments, and menisci; and for Dixon water‐fat imaging. In vivo T₂estimate repeatability and SNR efficiency for UTEDESS and Cartesian DESS were compared. The impact of coil combination methods on short‐T₂measurements was evaluated by means of simulations. UTEDESS T₂measurements were compared with T₂measurements from Cartesian DESS, multi‐echo spin‐echo (MESE), and fast spin‐echo (FSE).

   UTEDESS produced isotropic resolution images with high SNR efficiency in all short‐T₂tissues. Simulations and experiments demonstrated that sum‐of‐squares coil combinations overestimated short‐T₂measurements. UTEDESS measurements of meniscal T₂were comparable to DESS, MESE, and FSE measurements while the tendon and ligament measurements were less biased than those from Cartesian DESS. Average UTEDESS T₂repeatability variation was under 10% in all tissues.

   The T₂measurements of short‐T₂tissues and high‐resolution morphological imaging provided by UTEDESS makes it promising for studying the whole knee, both in routine clinical examinations and longitudinal studies. Magn Reson Med 78:2136–2148, 2017. © 2017 International Society for Magnetic Resonance in Medicine.

    

   more » « less