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1. Generalized Adjustment Under Confounding and Selection Biases

   Correa, J.; Tian, J.; Bareinboim, E. (January 2018, Proceedings of the 32nd AAAI Conference on Artificial Intelligence (AAAI))

   Selection and confounding biases are the two most common impediments to the applicability of causal inference methods in large-scale settings. We generalize the notion of backdoor adjustment to account for both biases and leverage external data that may be available without selection bias (e.g., data from census). We introduce the notion of adjustment pair and present complete graphical conditions for identifying causal effects by adjustment. We further design an algorithm for listing all admissible adjustment pairs in polynomial delay, which is useful for researchers interested in evaluating certain properties of some admissible pairs but not all (common properties include cost, variance, and feasibility to measure). Finally, we describe a statistical estimation procedure that can be performed once a set is known to be admissible, which entails different challenges in terms of finite samples. 

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2. Adjustment Criteria for Generalizing Experimental Findings

   Correa, J.; Tian, J.; Bareinboim, E. (January 2019, Proceedings of the 36th International Conference on Machine Learning (ICML))

   Generalizing causal effects from a controlled experiment to settings beyond the particular study population is arguably one of the central tasks found in empirical circles. While a proper design and careful execution of the experiment would support, under mild conditions, the validity of inferences about the population in which the experiment was conducted, two challenges make the extrapolation step to different populations somewhat involved, namely, transportability and sampling selection bias. The former is concerned with disparities in the distributions and causal mechanisms between the domain (i.e., settings, population, environment) where the experiment is conducted and where the inferences are intended; the latter with distortions in the sample’s proportions due to preferential selection of units into the study. In this paper, we investigate the assumptions and machinery necessary for using covariate adjustment to correct for the biases generated by both of these problems, and generalize experimental data to infer causal effects in a new domain. We derive complete graphical conditions to determine if a set of covariates is admissible for adjustment in this new setting. Building on the graphical characterization, we develop an efficient algorithm that enumerates all possible admissible sets with poly-time delay guarantee; this can be useful for when some variables are preferred over the others due to different costs or amenability to measurement. 

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3. Adjustment Criteria for Generalizing Experimental Findings

   Correa, Juan; Tian, Jin; Bareinboim, Elias (January 2019, Proceedings of the 36th International Conference on Machine Learning)

   Generalizing causal effects from a controlled experiment to settings beyond the particular study population is arguably one of the central tasks found in empirical circles. While a proper design and careful execution of the experiment would support, under mild conditions, the validity of inferences about the population in which the experiment was conducted, two challenges make the extrapolation step to different populations somewhat involved, namely, transportability and sampling selection bias. The former is concerned with disparities in the distributions and causal mechanisms between the domain (i.e., settings, population, environment) where the experiment is conducted and where the inferences are intended; the latter with distortions in the sample’s proportions due to preferential selection of units into the study. In this paper, we investigate the assumptions and machinery necessary for using \emph{covariate adjustment} to correct for the biases generated by both of these problems, and generalize experimental data to infer causal effects in a new domain. We derive complete graphical conditions to determine if a set of covariates is admissible for adjustment in this new setting. Building on the graphical characterization, we develop an efficient algorithm that enumerates all possible admissible sets with poly-time delay guarantee; this can be useful for when some variables are preferred over the others due to different costs or amenability to measurement. 

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4. Nonparametric identification of causal effects in clustered observational studies with differential selection

   https://doi.org/10.1093/jrsssa/qnae018  

   Ye, Ting; Westling, Ted; Page, Lindsay; Keele, Luke (March 2024, Journal of the Royal Statistical Society Series A: Statistics in Society)

   The clustered observational study (COS) design is the observational counterpart to the clustered randomized trial. COSs are common in both education and health services research. In education, treatments may be given to all students within some schools but withheld from all students in other schools. In health studies, treatments may be applied to clusters such as hospitals or groups of patients treated by the same physician. In this paper, we study the identification of causal effects in COS designs. We focus on the prospect of differential selection of units to clusters, which occurs when the units’ cluster selections depend on the clusters’ treatment assignments. Extant work on COSs has made an implicit assumption that rules out the presence of differential selection. We derive the identification results for designs with differential selection and that contexts with differential cluster selection require different adjustment sets than standard designs. We outline estimators for designs with and without differential selection. Using a series of simulations, we outline the magnitude of the bias that can occur with differential selection. We then present 2 empirical applications focusing on the likelihood of differential selection. 

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5. Identification of Causal Effects in the Presence of Selection Bias

   Correa, Juan; Tian, Jin; Bareinboim, Elias (January 2019, Proceedings of the 33rd AAAI Conference on Artificial Intelligence (AAAI), 2019.)

   Cause-and-effect relations are one of the most valuable types of knowledge sought after throughout the data-driven sciences since they translate into stable and generalizable explanations as well as efficient and robust decision-making capabilities. Inferring these relations from data, however, is a challenging task. Two of the most common barriers to this goal are known as confounding and selection biases. The former stems from the systematic bias introduced during the treat- ment assignment, while the latter comes from the systematic bias during the collection of units into the sample. In this paper, we consider the problem of identifiability of causal effects when both confounding and selection biases are simultaneously present. We first investigate the problem of identifiability when all the available data is biased. We prove that the algorithm proposed by [Bareinboim and Tian, 2015] is, in fact, complete, namely, whenever the algorithm returns a failure condition, no identifiability claim about the causal relation can be made by any other method. We then generalize this setting to when, in addition to the biased data, another piece of external data is available, without bias. It may be the case that a subset of the covariates could be measured without bias (e.g., from census). We examine the problem of identifiability when a combination of biased and unbiased data is available. We propose a new algorithm that subsumes the current state-of-the-art method based on the back-door criterion. 

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