More Like this

1. Regioselective lithiation of benzyl imidazole: Synthesis and evaluation of new organocatalysts for trans -diol functionalization.

   https://doi.org/10.1080/00397911.2019.1655766  

   El-Mansy, Mohamed ; Ghosh, Ankan ; Cheong, Paul Ha-Yeon ; Carter, Rich ( November 2019 , Synthetic Communications)
2. Identification of key functionalization species in the Cp*Ir( iii )-catalyzed- ortho halogenation of benzamides

   https://doi.org/10.1039/d0dt00565g  

   Guzmán Santiago, Alexis J. ; Brown, Caleb A. ; Sommer, Roger D. ; Ison, Elon A. ( January 2020 , Dalton Transactions)

   Cp*Ir( iii ) complexes have been shown to be effective for the halogenation of N , N -diisopropylbenzamides with N -halosuccinimide as a suitable halogen source. The optimized conditions for the iodination reaction consist of 0.5 mol% [Cp*IrCl 2 ] 2 in 1,2-dichloroethane at 60 °C for 1 h to form a variety of iodinated benzamides in high yields. Increasing the catalyst loading to 6 mol% and the time to 4 h enabled the bromination reaction of the same substrates. Reactivity was not observed for the chlorination of these substrates. A variety of functional groups on the para -position of the benzamide were well tolerated. Kinetic studies showed the reaction dependence is first order in iridium, positive order in benzamide, and zero order in N -iodosuccinimide. A KIE of 2.5 was obtained from an independent H/D kinetic isotope effect study. Computational studies (DFT-BP3PW91) indicate that a CMD mechanism is more likely than an oxidative addition pathway for the C–H bond activation step. The calculated functionalization step involves an Ir( v ) species that is the result of oxidative addition of acetate hypoiodite that is generated in situ from N -iodosuccinimide and acetic acid. 

   more » « less
3. In Situ Focused Ion Beam-Scanning Electron Microscope Study of Crack and Nanopore Formation in Germanium Particle During (De)lithiation

   https://doi.org/10.1021/acsaem.9b00380  

   Zhou, Xinwei ; Li, Tianyi ; Cui, Yi ; Meyerson, Melissa L. ; Mullins, C. Buddie ; Liu, Yuzi ; Zhu, Likun ( April 2019 , ACS Applied Energy Materials)
4. Anomalous ortho -Proton Acidities of the para -Haloanisoles: Anomalous ortho -Proton Acidities of the para -Haloanisoles

   https://doi.org/10.1002/ejoc.201701265  

   Slocum, D. W. ; Maulden, Emily A. ; Whitley, Paul E. ; Reinscheld, Thomas K. ; Jackson, Colleen S. ; Maddox, Jeremy B. ( December 2017 , European Journal of Organic Chemistry)
5. Identification of pyrolysis products of the new psychoactive substance 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone hydrochloride ( bk -2C-B) and its iodo analogue bk -2C-I: Pyrolysis of bk -2C-B and bk -2C-I

   https://doi.org/10.1002/dta.2200  

   Texter, Kelly B. ; Waymach, Rachel ; Kavanagh, Pierce V. ; O'Brien, John E. ; Talbot, Brian ; Brandt, Simon D. ; Gardner, Elizabeth A. ( January 2018 , Drug Testing and Analysis)