Every year about 1.5 million people have surgery to treat meniscal tears across the US and Europe. Traditionally, meniscus transplantation is the primary treatment in the long term. 3D printing is a substitute to the traditional transplantation method. With its previous contribution to tooth crowns, hearing aids and other life science industries, 3D printing has shown to be successful. In this article, we would like to investigate the feasibility of adopting 3D printing on meniscus in terms of supply chain cost and patient cost. We use data collected from online resources, literature citations and making assumptions where necessary. The analysis is carried in two directions: first, cost models for traditional transplantation and 3D printing-based transplantation in patients’ perspective are developed. Second, a hypothesized pathway model is created to analyze post-transplantation cost and risk for patients. Simulation based on the pathway model will be done to estimate parameters of the model. Meanwhile, we use a Markov model to study the potential post-transplantation risks which may induce additional cost to patients. Our results will help hospitals in making decisions on the introduction of 3D printing systems.
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Modeling-Based Assessment of 3D Printing-Enabled Meniscus Transplantation
3D printing technology is able to produce personalized artificial substitutes for patients with damaged menisci. However, there is a lack of thorough understanding of 3D printing-enabled (3DP-enabled) meniscus transplantation and its long-term advantages over traditional transplantation. To help health care stakeholders and patients assess the value of 3DP-enabled meniscus transplantation, this study compares the long-term cost and risk of this new paradigm with traditional transplantation by simulation. Pathway models are developed to simulate patients’ treatment process during a 20-year period, and a Markov process is used to model the state transitions of patients after transplantation. A sensitivity analysis is also conducted to show the effect of quality of 3D-printed meniscus on model outputs. The simulation results suggest that the performance of 3DP-enabled meniscus transplantation depends on quality of 3D-printed meniscus. The conclusion of this study is that 3DP-enabled meniscus transplantation has many advantages over traditional meniscus transplantation, including a minimal waiting time, perfect size and shape match, and potentially lower cost and risk in the long term.
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- Award ID(s):
- 1634858
- PAR ID:
- 10101533
- Date Published:
- Journal Name:
- Healthcare
- Volume:
- 7
- Issue:
- 2
- ISSN:
- 2227-9032
- Page Range / eLocation ID:
- 69
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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