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Title: Electrochemical C(sp3)–H Fluorination
A simple and robust method for electrochemical alkyl C–H fluorination is presented. Using a simple nitrate additive, a widely available fluorine source (Selectfluor), and carbon-based electrodes, a wide variety of activated and unactivated C–H bonds are converted into their C–F congeners. The scalability of the reaction is also demonstrated with a 100 gram preparation of fluorovaline.  more » « less
Award ID(s):
1740656
PAR ID:
10109642
Author(s) / Creator(s):
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Date Published:
Journal Name:
Synlett
Volume:
30
Issue:
10
ISSN:
0936-5214
Page Range / eLocation ID:
1178 to 1182
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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