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Abstract Visible light‐induced Pd catalysis has emerged as a promising subfield of photocatalysis. The hybrid nature of Pd radical species has enabled a wide array of radical‐based transformations otherwise challenging or unknown via conventional Pd chemistry. In parallel to the ongoing pursuit of alternative, readily available radical precursors, notable discoveries have demonstrated that photoexcitation can alter not only oxidative addition but also other elementary steps. This Minireview highlights the recent progress in this area.
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Visible-Light-Induced Dearomatizations: Visible-Light-Induced Dearomatizations
The dearomatization of aromatic compounds is an important synthetic strategy used in accessing complex three‐dimensional structures from simple aromatic precursors. This minireview aims to provide an overview of recent advancements in this area, with a specific focus on visible‐light‐mediated dearomative transformations. Compared to the conventional high‐energy ultraviolet (UV) light‐promoted processes, not only these new approaches offer milder reaction conditions to accommodate wider variety of substrates with sensitive functionalities, but also enable the use of photocatalysts and other promoters, significantly expanding the reaction space. Application of these transformations to the synthesis of bioactive compounds are also discussed.
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- Award ID(s):
- 1654110
- PAR ID:
- 10133126
- Date Published:
- Journal Name:
- European Journal of Organic Chemistry
- ISSN:
- 1434-193X
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript
- Journal Article:
- https://doi.org/10.1002/ejoc.201901229
