More Like this

1. OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology

   https://doi.org/10.1038/ncomms11542  

   Klimas, Aleksandra; Ambrosi, Christina M.; Yu, Jinzhu; Williams, John C.; Bien, Harold; Entcheva, Emilia (September 2016, Nature Communications)
2. The role of excitation vector fields and all-polarisation state control in cavity magnonics

   https://doi.org/10.1038/s44306-024-00062-z  

   Joseph, Alban; Nair, Jayakrishnan_M P; Smith, Mawgan A; Holland, Rory; McLellan, Luke J; Boventer, Isabella; Wolz, Tim; Bozhko, Dmytro A; Flebus, Benedetta; Weides, Martin P; et al (December 2024, npj Spintronics)

   Abstract Recently the field of cavity magnonics, a field focused on controlling the interaction between magnons and photons confined within microwave resonators, has drawn significant attention as it offers a platform for enabling advancements in quantum- and spin-based technologies. Here, we introduce excitation vector fields, whose polarisation and profile can be easily tuned in a two-port cavity setup, thus acting as an effective experimental dial to explore the coupled dynamics of cavity magnon-polaritons. Moreover, we develop theoretical models that accurately predict and reproduce the experimental results for any polarisation state and field profile within the cavity resonator. This versatile experimental platform offers a new avenue for controlling spin-photon interactions by manipulating the polarisation of excitation fields. By introducing real-time tunable parameters that control the polarisation state, our experiment delivers a mechanism to readily control the exchange of information between hybrid systems. 

   more » « less
3. Selective control of synaptically-connected circuit elements by all-optical synapses

   https://doi.org/10.1038/s42003-021-02981-7  

   Prakash, Mansi; Murphy, Jeremy; St Laurent, Robyn; Friedman, Nina; Crespo, Emmanuel L.; Bjorefeldt, Andreas; Pal, Akash; Bhagat, Yuvraj; Kauer, Julie A.; Shaner, Nathan C.; et al (January 2022, Communications Biology)

   Abstract Understanding percepts, engrams and actions requires methods for selectively modulating synaptic communication between specific subsets of interconnected cells. Here, we develop an approach to control synaptically connected elements using bioluminescent light: Luciferase-generated light, originating from a presynaptic axon terminal, modulates an opsin in its postsynaptic target. Vesicular-localized luciferase is released into the synaptic cleft in response to presynaptic activity, creating a real-time Optical Synapse. Light production is under experimenter-control by introduction of the small molecule luciferin. Signal transmission across this optical synapse is temporally defined by the presence of both the luciferin and presynaptic activity. We validate synaptic Interluminescence by multi-electrode recording in cultured neurons and in mice in vivo. Interluminescence represents a powerful approach to achieve synapse-specific and activity-dependent circuit control in vivo. 

   more » « less
4. Propagation of Parametric Uncertainty in Aliev-Panfilov Model of Cardiac Excitation

   Son, J. (July 2018, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC))
5. Propagation of Parametric Uncertainty in Aliev-Panfilov Model of Cardiac Excitation

   Son, J. (July 2018, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC))