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Title: Biodegradable Polyhydroxyalkanoates by Stereoselective Copolymerization of Racemic Diolides: Stereocontrol and Polyolefin‐Like Properties
Abstract

Bacterial polyhydroxyalkanoates (PHAs) are a unique class of biodegradable polymers because of their biodegradability in ambient environments and structural diversity enabled by side‐chain groups. However, the biosynthesis of PHAs is slow and expensive, limiting their broader applications as commodity plastics. To overcome such limitation, the catalyzed chemical synthesis of bacterial PHAs has been developed, using the metal‐catalyzed stereoselective ring‐opening (co)polymerization of racemic cyclic diolides (rac‐8DLR, R=alkyl group). In this combined experimental and computational study, polymerization kinetics, stereocontrol, copolymerization characteristics, and the properties of the resulting PHAs have been examined. Most notably, stereoselective copolymerizations ofrac‐8DLMewithrac‐8DLR(R=Et, Bu) have yielded high‐molecular‐weight, crystalline isotactic PHA copolymers that are hard, ductile, and tough plastics, and exhibit polyolefin‐like thermal and mechanical properties.

 
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NSF-PAR ID:
10148141
Author(s) / Creator(s):
 ;  ;  ;  ;  ;  
Publisher / Repository:
Wiley Blackwell (John Wiley & Sons)
Date Published:
Journal Name:
Angewandte Chemie International Edition
Volume:
59
Issue:
20
ISSN:
1433-7851
Page Range / eLocation ID:
p. 7881-7890
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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