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Title: Quantifying the effects of quadrupolar sinks via 15 N relaxation dynamics in metronidazoles hyperpolarized via SABRE-SHEATH
15 N spin–lattice relaxation dynamics in metronidazole- 15 N 3 and metronidazole- 15 N 2 isotopologues are studied for rational design of 15 N-enriched biomolecules for signal amplification by reversible exchange in microtesla fields. 15 N relaxation dynamics mapping reveals the deleterious effects of interactions with the polarization transfer catalyst and a quadrupolar 14 N nucleus within the spin-relayed 15 N– 15 N network.  more » « less
Award ID(s):
1904780 1905341
NSF-PAR ID:
10180976
Author(s) / Creator(s):
; ; ; ; ; ; ; ; ; ;
Date Published:
Journal Name:
Chemical Communications
ISSN:
1359-7345
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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