In this study, a 3D asymmetric lifting motion is predicted by using a hybrid predictive model to prevent potential musculoskeletal lower back injuries for asymmetric lifting tasks. The hybrid model has two modules: a skeletal module and an OpenSim musculoskeletal module. The skeletal module consists of a dynamic joint strength based 40 degrees of freedom spatial skeletal model. The skeletal module can predict the lifting motion, ground reaction forces (GRFs), and center of pressure (COP) trajectory using an inverse dynamics-based motion optimization method. The musculoskeletal module consists of a 324-muscle-actuated full-body lumbar spine model. Based on the predicted kinematics, GRFs and COP data from the skeletal module, the musculoskeletal module estimates muscle activations using static optimization and joint reaction forces through the joint reaction analysis tool in OpenSim. The predicted asymmetric motion and GRFs are validated with experimental data. Muscle activation results between the simulated and experimental EMG are also compared to validate the model. Finally, the shear and compression spine loads are compared to NIOSH recommended limits. The differences between asymmetric and symmetric liftings are also compared.
Trajectory optimization with musculoskeletal models can be used to reconstruct measured movements and to predict changes in movements in response to environmental changes. It enables an exhaustive analysis of joint angles, joint moments, ground reaction forces, and muscle forces, among others. However, its application is still limited to simplified problems in two dimensional space or straight motions. The simulation of movements with directional changes, e.g. curved running, requires detailed three dimensional models which lead to a high-dimensional solution space. We extended a full-body three dimensional musculoskeletal model to be specialized for running with directional changes. Model dynamics were implemented implicitly and trajectory optimization problems were solved with direct collocation to enable efficient computation. Standing, straight running, and curved running were simulated starting from a random initial guess to confirm the capabilities of our model and approach: efficacy, tracking and predictive power. Altogether the simulations required 1 h 17 min and corresponded well to the reference data. The prediction of curved running using straight running as tracking data revealed the necessity of avoiding interpenetration of body segments. In summary, the proposed formulation is able to efficiently predict a new motion task while preserving dynamic consistency. Hence, labor-intensive and thus costly experimental studies could be replaced by simulations for movement analysis and virtual product design.
more » « less- NSF-PAR ID:
- 10198419
- Publisher / Repository:
- Nature Publishing Group
- Date Published:
- Journal Name:
- Scientific Reports
- Volume:
- 10
- Issue:
- 1
- ISSN:
- 2045-2322
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
More Like this
-
more » « less
-
more » « less
Abstract In this study, a hybrid predictive model is used to predict 3D asymmetric lifting motion and assess potential musculoskeletal lower back injuries for asymmetric lifting tasks. The hybrid model has two modules: a skeletal module and an OpenSim musculoskeletal module. The skeletal module consists of a dynamic joint strength based 40 degrees of freedom spatial skeletal model. The skeletal module can predict the lifting motion, ground reaction forces (GRFs), and center of pressure (COP) trajectory using an inverse dynamics based optimization method. The equations of motion are built by recursive Lagrangian dynamics. The musculoskeletal module consists of a 324-muscle-actuated full-body lumbar spine model. Based on the generated kinematics, GRFs and COP data from the skeletal module, the musculoskeletal module estimates muscle activations using static optimization and joint reaction forces through the joint reaction analysis tool. Muscle activation results between simulated and experimental EMG are compared to validate the model. Finally, potential lower back injuries are evaluated for a specific-weight asymmetric lifting task. The shear and compression spine loads are compared to NIOSH recommended limits. At the beginning of the dynamic lifting process, the simulated compressive spine load beyond the NIOSH action limit but less than the permissible limit. This is due to the fatigue factors considered in NIOSH lifting equation.
-
null (Ed.)Abstract The domestic dog is interesting to investigate because of the wide range of body size, body mass, and physique in the many breeds. In the last several years, the number of clinical and biomechanical studies on dog locomotion has increased. However, the relationship between body structure and joint load during locomotion, as well as between joint load and degenerative diseases of the locomotor system (e.g. dysplasia), are not sufficiently understood. Collecting this data through in vivo measurements/records of joint forces and loads on deep/small muscles is complex, invasive, and sometimes unethical. The use of detailed musculoskeletal models may help fill the knowledge gap. We describe here the methods we used to create a detailed musculoskeletal model with 84 degrees of freedom and 134 muscles. Our model has three key-features: three-dimensionality, scalability, and modularity. We tested the validity of the model by identifying forelimb muscle synergies of a walking Beagle. We used inverse dynamics and static optimization to estimate muscle activations based on experimental data. We identified three muscle synergy groups by using hierarchical clustering. The activation patterns predicted from the model exhibit good agreement with experimental data for most of the forelimb muscles. We expect that our model will speed up the analysis of how body size, physique, agility, and disease influence neuronal control and joint loading in dog locomotion.more » « less
-
more » « less
Computer modeling, simulation and optimization are powerful tools that have seen increased use in biomechanics research. Dynamic optimizations can be categorized as either data-tracking or predictive problems. The data-tracking approach has been used extensively to address human movement problems of clinical relevance. The predictive approach also holds great promise, but has seen limited use in clinical applications. Enhanced software tools would facilitate the application of predictive musculoskeletal simulations to clinically-relevant research. The open-source software OpenSim provides tools for generating tracking simulations but not predictive simulations. However, OpenSim includes an extensive application programming interface that permits extending its capabilities with scripting languages such as MATLAB. In the work presented here, we combine the computational tools provided by MATLAB with the musculoskeletal modeling capabilities of OpenSim to create a framework for generating predictive simulations of musculoskeletal movement based on direct collocation optimal control techniques. In many cases, the direct collocation approach can be used to solve optimal control problems considerably faster than traditional shooting methods. Cyclical and discrete movement problems were solved using a simple 1 degree of freedom musculoskeletal model and a model of the human lower limb, respectively. The problems could be solved in reasonable amounts of time (several seconds to 1–2 hours) using the open-source IPOPT solver. The problems could also be solved using the fmincon solver that is included with MATLAB, but the computation times were excessively long for all but the smallest of problems. The performance advantage for IPOPT was derived primarily by exploiting sparsity in the constraints Jacobian. The framework presented here provides a powerful and flexible approach for generating optimal control simulations of musculoskeletal movement using OpenSim and MATLAB. This should allow researchers to more readily use predictive simulation as a tool to address clinical conditions that limit human mobility.
-
This article presents an optimization formulation and experimental validation of a dynamic-joint-strength-based two-dimensional symmetric maximum weight-lifting simulation. Dynamic joint strength (the net moment capacity as a function of joint angle and angular velocity), as presented in the literature, is adopted in the optimization formulation to predict the symmetric maximum lifting weight and corresponding motion. Nineteen participants were recruited to perform a maximum-weight-box-lifting task in the laboratory, and kinetic and kinematic data including motion and ground reaction forces were collected using a motion capture system and force plates, respectively. For each individual, the predicted spine, shoulder, elbow, hip, knee, and ankle joint angles, as well as vertical and horizontal ground reaction force and box weight, were compared with the experimental data. Both root-mean-square error and Pearson’s correlation coefficient ( r) were used for the validation. The results show that the proposed two-dimensional optimization-based motion prediction formulation is able to accurately predict all joint angles, box weights, and vertical ground reaction forces, but not horizontal ground reaction forces.more » « less
