Heritable variation in gene expression is common within and among species and contributes to phenotypic diversity. Mutations affecting either
This article is part of the theme issue ‘Interdisciplinary approaches to predicting evolutionary biology’.
The role of mutations of large effect in adaptive evolution is a question of enduring interest. Large-effect mutations were once seen as unlikely contributors to adaptation, but we now have numerous examples. A major shortcoming of the evidence is the lack of information on fitness effects of mutations. We conducted a quantitative trait locus study that mapped fitness in an experimental field population of stickleback to a large-effect gene,
- PAR ID:
- 10209141
- Publisher / Repository:
- Proceedings of the National Academy of Sciences
- Date Published:
- Journal Name:
- Proceedings of the National Academy of Sciences
- Volume:
- 118
- Issue:
- 3
- ISSN:
- 0027-8424
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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