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Title: Intrinsically Disordered Regions of the DNA-Binding Domain of Human FoxP1 Facilitate Domain Swapping
Award ID(s):
1749778
PAR ID:
10215738
Author(s) / Creator(s):
; ; ; ; ; ;
Date Published:
Journal Name:
Journal of Molecular Biology
Volume:
432
Issue:
19
ISSN:
0022-2836
Page Range / eLocation ID:
5411 to 5429
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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  1. Given the fundamental role of working memory (WM) in all domains of cognition, a central question has been whether WM is domain-general. However, the term ‘domain-general’ has been used in different, and sometimes misleading, ways. By reviewing recent evidence and biologically plausible models of WM, we show that the level of domain-generality varies substantially between three facets of WM: in terms of computations, WM is largely domain-general. In terms of neural correlates, it contains both domain-general and domain-specific elements. Finally, in terms of application, it is mostly domain-specific. This variance encourages a shift of focus towards uncovering domain-general computational principles and away from domain-general approaches to the analysis of individual differences and WM training, favoring newer perspectives, such as training-as-skill-learning. 
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  2. null (Ed.)