skip to main content

Title: Sexual signaling pattern correlates with habitat pattern in visually ornamented fishes
Award ID(s):
Author(s) / Creator(s):
; ;
Date Published:
Journal Name:
Nature Communications
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. Neuromodulators play an important role in how the nervous system organizes activity that results in behavior. Disruption of the normal patterns of neuromodulatory release or production is known to be related to the onset of severe pathologies such as Parkinson’s disease, Rett syndrome, Alzheimer’s disease, and affective disorders. Some of these pathologies involve neuronal structures that are called central pattern generators (CPGs), which are involved in the production of rhythmic activities throughout the nervous system. Here I discuss the interplay between CPGs and neuromodulatory activity, with particular emphasis on the potential role of neuromodulators in the recovery of disrupted neuronal activity. I refer to invertebrate and vertebrate model systems and some of the lessons we have learned from research on these systems and propose a few avenues for future research. I make one suggestion that may guide future research in the field: neuromodulators restrict the parameter landscape in which CPG components operate, and the removal of neuromodulators may enable a perturbed CPG in finding a new set of parameter values that can allow it to regain normal function. 
    more » « less
  2. Risk patterns are crucial in biomedical research and have served as an important factor in precision health and disease prevention. Despite recent development in parallel and high-performance computing, existing risk pattern mining methods still struggle with problems caused by large-scale datasets, such as redundant candidate generation, inability to discover long significant patterns, and prolonged post pattern filtering. In this article, we propose a novel dynamic tree structure, Risk Hierarchical Pattern Tree (RHPTree), and a top-down search method, RHPSearch, which are capable of efficiently analyzing a large volume of data and overcoming the limitations of previous works. The dynamic nature of the RHPTree avoids costly tree reconstruction for the iterative search process and dataset updates. We also introduce two specialized search methods, the extended target search (RHPSearch-TS) and the parallel search approach (RHPSearch-SD), to further speed up the retrieval of certain items of interest. Experiments on both UCI machine learning datasets and sampled datasets of the Simons Foundation Autism Research Initiative (SFARI)—Simon’s Simplex Collection (SSC) datasets demonstrate that our method is not only faster but also more effective in identifying comprehensive long risk patterns than existing works. Moreover, the proposed new tree structure is generic and applicable to other pattern mining problems. 
    more » « less
  3. null (Ed.)
    Abstract The timing of melt onset in the Arctic plays a key role in the evolution of sea ice throughout Spring, Summer and Autumn. A major catalyst of early melt onset is increased downwelling longwave radiation, associated with increased levels of moisture in the atmosphere. Determining the atmospheric moisture pathways that are tied to increased downwelling longwave radiation and melt onset is therefore of keen interest. We employed Self Organizing Maps (SOM) on the daily sea level pressure for the period 1979–2018 over the Arctic during the melt season (April–July) and identified distinct circulation patterns. Melt onset dates were mapped on to these SOM patterns. The dominant moisture transport to much of the Arctic is enabled by a broad low pressure region stretching over Siberia and a high pressure over northern North America and Greenland. This configuration, which is reminiscent of the North American-Eurasian Arctic dipole pattern, funnels moisture from lower latitudes and through the Bering and Chukchi Seas. Other leading patterns are variations of this which transport moisture from North America and the Atlantic to the Central Arctic and Canadian Arctic Archipelago. Our analysis further indicates that most of the early and late melt onset timings in the Arctic are strongly related to the strong and weak emergence of these preferred circulation patterns, respectively. 
    more » « less