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			<titleStmt><title level='a'>On the Enhancement of Heat Transfer and Reduction of Entropy Generation by Asymmetric Slip in Pressure-Driven Non-Newtonian Microflows</title></titleStmt>
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				<publisher></publisher>
				<date>02/01/2019</date>
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				<bibl> 
					<idno type="par_id">10251202</idno>
					<idno type="doi">10.1115/1.4042157</idno>
					<title level='j'>Journal of Heat Transfer</title>
<idno>0022-1481</idno>
<biblScope unit="volume">141</biblScope>
<biblScope unit="issue">2</biblScope>					

					<author>Vishal Anand</author><author>Ivan C. Christov</author>
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			<abstract><ab><![CDATA[We study hydrodynamics, heat transfer, and entropy generation in pressure-driven microchannel flow of a power-law fluid. Specifically, we address the effect of asymmetry in the slip boundary condition at the channel walls. Constant, uniform but unequal heat fluxes are imposed at the walls in this thermally developed flow. The effect of asymmetric slip on the velocity profile, on the wall shear stress, on the temperature distribution, on the Bejan number profiles, and on the average entropy generation and the Nusselt number are established through the numerical evaluation of exact analytical expressions derived. Specifically, due to asymmetric slip, the fluid momentum flux and thermal energy flux are enhanced along the wall with larger slip, which, in turn, shifts the location of the velocity's maximum to an off-center location closer to the said wall. Asymmetric slip is also shown to redistribute the peaks and plateaus of the Bejan number profile across the microchannel, showing a sharp transition between entropy generation due to heat transfer and due to fluid flow at an off-center-line location. In the presence of asymmetric slip, the difference in the imposed heat fluxes leads to starkly different Bejan number profiles depending on which wall is hotter, and whether the fluid is shear-thinning or shear-thickening. Overall, slip is shown to promote uniformity in both the velocity field and the temperature field, thereby reducing irreversibility in this flow.]]></ab></abstract>
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<div xmlns="http://www.tei-c.org/ns/1.0"><head n="1">Introduction</head><p>Contrary to what we teach in undergraduate fluid mechanics, the velocity of a fluid at a surface may or may not be equal to the velocity of said surface. This discontinuity in velocity at a fluid-solid interface is known as slip. Slip flow is encountered in industrial hydrodynamic processes across many length scales <ref type="bibr">[1]</ref>. At the macro-scale, slip flow occurs in extrusion of polymers, wherein it is caused by stress instabilities, * Author to whom correspondence should be addressed. and affects the quality of final product <ref type="bibr">[2]</ref>. At the micro-and nanoscale, slip flow is even more common <ref type="bibr">[3]</ref>. For microscale flow of rarefied gases, a dimensionless number, termed the Knudsen number, which is the ratio of the mean free path of the gas molecules to a characteristic channel dimension, determines the flow regime. When 0.001 &lt; Kn &lt; 0.1, the flow can still be treated in a continuum sense as long as slip at boundaries ("slip flow") is allowed <ref type="bibr">[4]</ref>. Here, the slip velocity boundary condition may also be accompanied by a temperature jump boundary condition, wherein there is a discontinuity in temperature at the fluid-solid interface <ref type="bibr">[3,</ref><ref type="bibr">5]</ref>. Although less common than in gases, slip flow may still be observed in microflows of liquids, when the surface of the channel is made of a hydrophobic material, or when the surface has microscale features such as roughness <ref type="bibr">[1]</ref>.</p><p>At the macro-scale, on the other hand, Denn <ref type="bibr">[2,</ref><ref type="bibr">6]</ref> provides a review of slip flows of non-Newtonian fluids, specifically polymer melts, while Kalyon <ref type="bibr">[7]</ref> discusses the apparent slip of concentrated suspensions. On the basis of molecular dynamics simulations, <ref type="bibr">Thompson and Troian [8]</ref> substantiated a generalized nonlinear slip boundary condition in which the slip length is a function of the shear rate, thereby generalizing the original slip law of Navier <ref type="bibr">[9]</ref>. More recently, Cloitre and Bonnecaze <ref type="bibr">[10]</ref> summarized the experimental approaches and evidence for nonlinear slip in flows of soft materials. Mathews and Hill <ref type="bibr">[11]</ref> initiated the theoretical work on Newtonian fluids subject to a nonlinear slip boundary condition by finding, analytically, the velocity profile for three canonical pressure-driven flows: in a pipe, in an annulus and in a channel.</p><p>From the early works of Bird, Acrivos et al. <ref type="bibr">[12,</ref><ref type="bibr">13]</ref> on flow and heat transfer of non-Newtonian fluids to the more "exotic" modern applications such as flow in self-affine subsurface fractures <ref type="bibr">[14]</ref>, the power-law fluid model (also known as the Ostwald-de Waele model) is a good starting point for modeling non-Newtonian fluid behavior, in part due to the power-law fluid's well-characterized material properties. Therefore, we restrict ourselves to this class of non-Newtonian fluids, which Bird featured as one of several selected "useful non-Newtonian models" <ref type="bibr">[15]</ref>. Thus, relevant to our present work is the analytical and semi-analytical study by Ferras et al. <ref type="bibr">[16]</ref> of the Couette-Poiseuille flow of Newtonian and generalized Newtonian fluids. Specifically, they obtained mathematical expressions for the velocity profiles for different types of inelastic fluids (e.g., power-law and Bingham fluids), for pressuredriven flows with either imposed pressure drop or imposed flow rate. Meanwhile, Pritchard et al. <ref type="bibr">[17]</ref> provide an overview and some new results regarding the development of unsteady unidirectional flow of power-law fluids, specifically Stokes' second problem of the oscillating plate. More recently, Wei and Jordan <ref type="bibr">[18]</ref> derived exact solutions for various traveling wave forms in compressible power-law fluids.</p><p>Transport in microchannels is an active area of research, especially in the heat transfer community, in particular due to the numerous applications related to the cooling of microelectronics <ref type="bibr">[19]</ref>. However, much of the research summarized in the authoritative reviews <ref type="bibr">[19,</ref><ref type="bibr">20]</ref> is on Newtonian working fluids, though slip effects are mentioned to be important in some flow regimes. On the other hand, though non-Newtonian fluids play a critical role in unconventional energy applications such as hydraulic fracturing <ref type="bibr">[21]</ref>, wherein slip and shearthinning/thickening can be observed, thermal effects have not been addressed in detail. As for the heat transfer characteristics of non-Newtonian fluids, Barletta <ref type="bibr">[22]</ref> proposed a new expression for the Brinkman number for power-law fluids, which is a dimensionless number that quantifies viscous dissipation, in his study of fully developed laminar convection of a powerlaw fluid with viscous dissipation. The Nusselt number correlations (and their method of computation) in laminar heat transfer of non-Newtonian fluids is of practical interest <ref type="bibr">[23]</ref>. Jambal et al. <ref type="bibr">[24]</ref> incorporated the effect of axial wall conduction in laminar convection of a power-law fluid with uniform wall temperature, deriving scalings for the Nusselt and Brinkman numbers in the thermal entrance region. Tso et al. <ref type="bibr">[25]</ref> considered the effect of asymmetric heat flux and viscous dissipation on heat transfer characteristics of fully developed flow of power-law fluids, showing that, for the case of unequal heat fluxes on the microchannel walls, the Nusselt number depends the Brinkman number. Meanwhile, Sheela-Fransisca et al. <ref type="bibr">[26]</ref> derived mathematical expressions relating the Nusselt number to the Brinkman number in the asymmetric thermal viscous-dissipative Couette-Poiseuille flow of a pseudo-plastic fluid. Additionally, Straughan <ref type="bibr">[27,</ref><ref type="bibr">Chap. 9]</ref> provides an excellent overview of the effects of the Navier slip condition on various heat transfer phenomena in Newtonian fluids. Kaushik et al. <ref type="bibr">[28]</ref> studied numerically the fluid dynamics, heat transfer and entropy generation characteristics of extrusion flows of power-law fluids between parallel plates under the lubrication approximation in quasi-steady state. They concluded that Nusselt number increases/decreases with time for shear-thinning/thickening fluids. For shear-thickening fluids, they observed unusual negative values of the Nusselt number. Sefid et al. <ref type="bibr">[29]</ref> presented numerical results on the thermal characteristics of developing and developed flow of power-law fluids in concentric annuli, demonstrating the entrance length's increases with the power-law index.</p><p>Beyond the heat transfer, it is of interest to also quantify the amount of entropy generated in a fluid system because, according to the Gouy-Studola theorem, the latter determines the work lost in the thermomechanical process <ref type="bibr">[30]</ref>. At the microscale, the velocity and temperature gradients encountered are larger than at the macroscale, which motivates us to additionally undertake the analysis of entropy generation of such thermal systems <ref type="bibr">[30]</ref>. Previously, Mahmud and Fraser <ref type="bibr">[31,</ref><ref type="bibr">32]</ref> minimized the entropy generated as a function of the powerlaw index in the flow between parallel plates <ref type="bibr">[31]</ref> and in a circular tube <ref type="bibr">[32]</ref>. Hung <ref type="bibr">[33]</ref> extended the latter to include viscous dissipation, showing that the rate of entropy generation increases with the Brinkman number, and this enhancement is more pronounced for shear-thickening fluids. Shojaeian et al. <ref type="bibr">[34]</ref> studied the effect of slip flow (under the linear Navier slip wall) on heat transfer and entropy generation characteristics of Newtonian and power-law fluids in microchannels. They found that the Nusselt number increases with slip, and this increase is, once again, more prominent for shear-thickening than shear-thinning fluids. Anand <ref type="bibr">[35]</ref> studied how the choice of a slip law influences the entropy generation and heat transfer characteristics of pressure-driven flow of a power-law fluid. He considered three slip laws for his study, namely, Navier's slip law, Hatzikiriakos' slip law, and the asymptotic slip law. He showed that, for the same slip coefficient, the Hatzikiriakos slip law predicts a higher Nusselt number and less entropy generation compared to the asymptotic slip law. Goswami et al. <ref type="bibr">[36]</ref> studied the entropy generation minimization of an electrosmotic flow of a power-law fluid taking into account the conjugate heat transfer. They derived approximate analytical solutions and concluded that the entropy generation has an optimum (minimum) value for a certain combination of wall thickness, wall thermal conductivity, and Biot number. Meanwhile, Mondal <ref type="bibr">[37]</ref> studied entropy generation in the combined Poiseuille-Couette flow of a power-law fluid between two asymmetrically heated plates. He found that irreversibility in shear-thinning fluids is primarily due to fluid friction, while it is primarily due to heat transfer in shear-thickening fluids. Viscous heating was also considered, finding that the Nusselt number suffers a singularity for negative Brinkman numbers due to a balance between the viscous dissipation in the fluid by heat transfer from the walls.</p><p>The existing literature dealing with slip flows assumes that the slip is identical on both walls of a channel. However, such symmetry is not necessarily always present. If the two channel walls are made from different materials (e.g., one is made from a polymer such as polydimethylsiloxane (PDMS), while the other is made from glass) or each has a different surface roughness, then asymmetric slip occurs. A similar situation occurs in the subsurface, wherein non-Newtonian fluids are pumped through complex fractured rocks with highly heterogeneous surface properties <ref type="bibr">[21]</ref>. Vayssade et al. <ref type="bibr">[38]</ref> performed an experimental study of suspension flow in a microchannel, providing evidence for asymmetric slip velocities along the channel walls. Panaseti et al. <ref type="bibr">[39]</ref> extended the latter approach, which was based on the Herschel-Bulkley (HB) fluid model, to account for slip via Navier's nonlinear slip condition. How-ever, thermal effects in such flows have not been considered.</p><p>The present work aims to address the latter apparent gap in the archival literature. Here, we address the effect of asymmetric slip boundary conditions on the hydrodynamics, heat transfer and the entropy generation characteristics of thermally fully developed flow of a power-law fluid in a microchannel under uniform heat flux thermal boundary conditions. Following <ref type="bibr">[16,</ref><ref type="bibr">35]</ref>, we implement the slip boundary condition using Navier's nonlinear slip law <ref type="bibr">[11]</ref>. We show, through a comparative analysis in Sect. 3, that asymmetry in the slip velocities at the channel walls has a significant influence on the fluid flow and the heat transfer characteristics of the problem, specifically on the enhancement of heat transfer and the reduction of irreversibility as compared to the usual case of symmetric slip boundary conditions. Our approach is analytical, based on the exact results that we first obtain in Sect. 2 for the fluid flow, heat transfer and entropy generation in a microchannel with asymmetric imposed heat fluxes and unequal wall slip coefficients.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="2">Problem statement and mathematical analysis</head><p>As Stone notes, "the equations [of fluid mechanics] are generally difficult to solve, (rational) approximations are necessary and frequently the interplay of physical arguments, mathematical simplifications, and experimental insights are crucial to progress and understanding" <ref type="bibr">[40]</ref>. To this end, we would like to pose a tractable problem of non-Newtonian fluid flow and heat transfer in the presence of asymmetric wall slip. Specifically, we consider the pressure-driven flow in a microchannel as shown in Fig. <ref type="figure">1</ref>. Although a "model flow" from the engineering point-of-view, understanding this basic flow is of fundamental interest as it is relevant to any context in which there is a separation of scales between a "small" cross-sectional and a "long" flow-wise direction (see, e.g., the discussion in <ref type="bibr">[40,</ref><ref type="bibr">Sect. 1.8.2]</ref>). In Fig. <ref type="figure">1</ref>, the microchannel is of height H, the lower wall is labeled "1," and the upper wall is labeled "2." The flow is maintained by constant pressure gradient G. 1 The lower and upper walls are each subject to a uniform and constant heat flux q 1 and q 2 , respectively. The slip coefficient, the meaning of which will be made clear through Eq. ( <ref type="formula">6</ref>) below, on the lower wall is K 1 , while on the upper wall it is K 2 . The x-axis is along the lower wall of the channel, in the flow-wise direction, while the y-axis is perpendicular to the lower wall, in the span-wise direction.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="2.1">Stress distribution</head><p>For a steady unidirectional flow in the x-direction, specifically v = u(y), 0, 0 , the conservation of linear momentum becomes <ref type="bibr">[41]</ref>:</p><p>1 To be precise, G is the inlet-outlet pressure difference per unit length of channel.</p><p>wall "1" wall "2" uniform heat flux q 2 uniform heat flux q 1 y x H u(y) where G is the pressure gradient and &#964; yx is the relevant component of the shear stress tensor &#964;. Alternatively, restricting to flow in a microchannel, the inertial forces can be neglected in comparison to the viscous and pressure forces, which once again yields Eq. ( <ref type="formula">1</ref>). Integrating Eq. ( <ref type="formula">1</ref>) with respect to y, we obtain</p><p>where C is an integration constant to be determined. At the lower wall (wall "1" at y = 0), the shear stress is given by &#964; w1 , i.e., &#964; yx | y=0 = &#964; w1 . Then, C = &#964; w1 and Eq. ( <ref type="formula">2</ref>) becomes</p><p>whence the shear stress on the top wall (wall "2" at y = H) is found to be</p><p>In what follows, it will be necessary to know the vertical location, y = y 0 , in the span-wise direction of the channel at which &#964; yx = 0 (i.e., where the shear stress vanishes and the velocity gradient changes sign). This location is obtained by setting the right-hand side of Eq. (3) to zero, which yields</p><p>The slip boundary condition can be understood as "coupling between the local velocity and the surface stresses" <ref type="bibr">[40,</ref><ref type="bibr">Sect. 1.4.1]</ref>. Specifically, the slip velocity at a given wall can be expressed in terms of the shear stress at that wall. Following <ref type="bibr">[11,</ref><ref type="bibr">16]</ref>, we employ Navier's nonlinear slip law. The slip velocity at wall "1" and wall "2" are then denoted by u w1 and u w2 , respectively. Thus, the velocity-stress relation at the channel walls takes the form (see also <ref type="bibr">[10,</ref><ref type="bibr">Eq. (5)</ref>] and the discussion thereof):</p><p>where K 1 and K 2 are the slip coefficients and m is the slip exponent. For m = 1, Navier's (linear) slip law [9, 1] is obtained.</p><p>The slip coefficients and the slip exponent depend on various physical factors such as dissolved phases in the fluid, wall surface roughness and wetting properties, electro-rheological behavior of the fluid, etc. <ref type="bibr">[1]</ref>. In the present work, we consider the slip to be asymmetric, i.e., K 1 K 2 , but we assume that the slip exponent m is the same on both walls (see, e.g., <ref type="bibr">[38]</ref>).</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="2.2">Velocity distribution</head><p>Next, we seek to determine the velocity distribution across the microchannel, which is sketched representatively in Fig. <ref type="figure">1</ref>. To that end, we first need to prescribe the constitutive equation for the fluid. In the present work, following <ref type="bibr">[35,</ref><ref type="bibr">16,</ref><ref type="bibr">42]</ref>, we consider the fluid to be non-Newtonian and its shear stress-strain rate relationship to be well-described by the power-law model <ref type="bibr">[43]</ref>. For unidirectional flow, the latter relationship takes the form</p><p>Here, a is the consistency factor, while n is the power-law index. According to the power-law model, when n &lt; 1, the apparent viscosity, &#951; = a|du/dy| n-1 , of the fluid decreases with the shear rate-of-strain, and such a fluid is termed shearthinning. On the other hand, when n &gt; 1, the apparent viscosity of the fluid increases with the shear rate-of-strain, and such a fluid is termed shear-thickening. The power-law model in Eq. ( <ref type="formula">7</ref>) reduces to Newton's law of viscosity for n = 1, in which case a becomes the usual shear viscosity.</p><p>In the lower portion of the microchannel, y &lt; y 0 and du/dy &gt; 0, which allows us to write Eq. ( <ref type="formula">7</ref>) for shear stress as</p><p>Substituting the latter into Eq. ( <ref type="formula">3</ref>), yields the following firstorder ordinary differential equation (ODE) for u(y):</p><p>The latter ODE is easily integrated to give</p><p>where C 1 is an arbitrary constant of integration. The boundary condition u(0) = u w1 allows us to solve for the integration constant:</p><p>Thus, the expression for velocity distribution in the strip 0 &#8804; y &lt; y 0 is</p><p>In the upper portion of the microchannel, y &gt; y 0 and du/dy &lt; 0, which allows us to, now, write Eq. ( <ref type="formula">7</ref>) for the shear stress as</p><p>Substituting the latter into Eq. ( <ref type="formula">3</ref>), again yields a first-order ODE for u(y):</p><p>which is easily integrated to obtain</p><p>The integration constant C 2 is set by the boundary condition at wall 2, i.e., u(H) = u w2 :</p><p>Thus, the expression for velocity distribution in the strip</p><p>All quantities of interest have been written in terms of &#964; w1 , which is the only unknown remaining now. To find an expression for &#964; w1 , we must require that the velocity profile u(y) be continuous across y = y 0 :</p><p>Thus, upon substituting Eq. ( <ref type="formula">5</ref>) for y 0 and Eqs. ( <ref type="formula">6</ref>) for u w1 and u w2 into Eqs. ( <ref type="formula">12</ref>) and ( <ref type="formula">17</ref>), we obtain</p><p>Equation ( <ref type="formula">19</ref>) is an implicit, nonlinear algebraic equation for &#964; w1 given K 1 , K 2 , G, a, n and H. In practice, it must be inverted numerically. Nevertheless, this completes the derivation of the unidirectional velocity profile u(y) of a power-law fluid in a microchannel with asymmetric slip. To summarize: u(y) is piecewise defined by Eqs. ( <ref type="formula">12</ref>) and ( <ref type="formula">17</ref>) and &#964; w1 is found by solving Eq. ( <ref type="formula">19</ref>) numerically.</p><p>From the above equations, some characteristic physical scales are evident. The characteristic length scale in the problem is &#8467; c = H. The pressure gradient then sets a character stress scale T c = G&#8467; c = GH and a characteristic velocity scale is evident from Eqs. ( <ref type="formula">12</ref>) and ( <ref type="formula">17</ref>):</p><p>Hence, we are led to introduce the following dimensionless variables:</p><p>Using the latter set of dimensionless variables, we obtain a set of dimensionless, coupled nonlinear algebraic equations that fully specify the velocity profile:</p><p>where Navier's nonlinear slip law gives</p><p>and &#964;w1 satisfies</p><p>As a consistency check, note that, for the special case of symmetric slip with K1 = K2 , &#964;w1 = 1/2 is obviously a solution of Eq. ( <ref type="formula">26</ref>). Therefore, for symmetric slip, the velocity gradient vanishes exactly along the channel's centerline. Note that the velocity profile for a power-law fluid with asymmetric slip developed above, i.e., Eqs. ( <ref type="formula">24</ref>)-( <ref type="formula">26</ref>), was also considered in [39, Eq. ( <ref type="formula">23</ref>)-( <ref type="formula">25</ref>)], wherein the power-law fluid is a special case of a derivation for HB fluids. Of course, in showing an equivalence, one has to take into account the different characteristic scales employed in <ref type="bibr">[39]</ref>.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="2.3">Temperature distribution</head><p>The energy equation for the thermally developed flow of a power-law fluid in a microchannel (see, e.g., <ref type="bibr">[33,</ref><ref type="bibr">35]</ref> and the references therein) is given by</p><p>where viscous dissipation cannot be neglected for microflows, as discussed by Koo and Kleinstreuer <ref type="bibr">[44]</ref>. Here &#961;, c p , k are respectively the density, specific heat and thermal conductivity of the fluid, which are assumed constant for this problem, and T (x, y) is the temperature profile in the microchannel. Let us introduce the dimensionless temperature</p><p>where, following our convention for the velocity profile, we denote the temperature profiles on the lower and upper channel walls as T w1 (x) &#8801; T (x, 0) and T w2 (x) &#8801; T (x, H), respectively. We also note that although &#8706;T /&#8706; x 0 [see Eqs. ( <ref type="formula">31</ref>) and ( <ref type="formula">35</ref>) below], &#8706;&#952;/&#8706; x = 0, i.e., &#952; = &#952;( &#563;) only, because of the assumption of thermally developed flow under uniform heat flux boundary conditions (see also <ref type="bibr">[45,</ref><ref type="bibr">Chap. 8]</ref>). Then, the energy equation ( <ref type="formula">27</ref>) becomes:</p><p>where recall that V c is the characteristic fluid velocity as in Eq. ( <ref type="formula">22</ref>) above, and Br &#8242; is a modified Brinkman number for power-law fluids <ref type="bibr">[22]</ref>:</p><p>Br &#8242; is a measure of the relative importance of viscous dissipation in the flow compared to the imposed (constant) heat flux. Next, note that the quantity in the parentheses on the lefthand side of Eq. ( <ref type="formula">29</ref>) is, in fact, dimensionless. Under our assumption of uniform heat flux being supplied through the upper and lower walls of the microchannel (recall Fig. <ref type="figure">1</ref> and the attendant discussion), we shall show that this quantity is, additionally, constant. First, let</p><p>At this stage in the analysis &#947; is unknown but will be determined shortly. Nevertheless, let us write Eq. ( <ref type="formula">29</ref>) as</p><p>The pertinent boundary conditions for Eq. ( <ref type="formula">32</ref>) are</p><p>Although Eq. ( <ref type="formula">32</ref>) is of second order in &#563;, we need the three boundary conditions in Eqs. <ref type="bibr">(33)</ref> to fully specify the problem because, at this point, &#947; is still unknown. Now, we are in a position to solve for &#947; by integrating Eq. ( <ref type="formula">32</ref>) with respect to &#563; across the channel height:</p><p>(34) Solving for &#947; and using the boundary conditions from Eqs. <ref type="bibr">(33)</ref>, we obtain:</p><p>The definite integrals in Eq. ( <ref type="formula">35</ref>) can be evaluated exactly based on the velocity profile given in Eq. ( <ref type="formula">24</ref>); the resulting expressions are given in A. Now, &#947; is substituted into Eq. ( <ref type="formula">32</ref>), reducing the latter equation to an ODE in &#952;, which can be easily solved via standard numerical integration techniques.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="2.4">Nusselt number</head><p>The literature on convective heat transfer and fluid mechanics is full of important dimensionless parameters <ref type="bibr">[45]</ref>. Amongst the more useful ones in convection heat transfer, and the first one we encounter herein, is the Nusselt number. In fully developed flow, it is customary to utilize the mean temperature T m as opposed to the centerline temperature for the definition of the Nusselt number. The mean temperature is given by</p><p>Thus, the dimensionless mean temperature is</p><p>which is, again, independent of x based on the foregoing discussion. Now, the heat transfer coefficient (HTC) based on the mean temperature of the fluid can be defined as</p><p>Finally, the Nusselt number (for flow between parallel plates) is simply the dimensionless heat transfer coefficient:</p><p>Using the temperature profile obtained by numerically integrating the ODE (32) and the analytical velocity profile from Eq. ( <ref type="formula">24</ref>), Nu can be evaluated numerically directly from Eq. (39).</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="2.5">Entropy generation</head><p>The expression for volumetric entropy generation due to convection heat transfer with viscous dissipation included (see, e.g., <ref type="bibr">[35]</ref>) in a power-law fluid is given by</p><p>The dimensionless form of Eq. ( <ref type="formula">40</ref>) is</p><p>Here,</p><p>is the dimensionless heat flux, and</p><p>is the P&#233;clet number. We are interested in the limit Pe &#8811; 1, hence the first term in Eq. ( <ref type="formula">40</ref>) can be neglected, consistent with our assumption of a fully developed thermal field. Then, we obtain the following simplified expression for the dimensionless entropy generation:</p><p>The first term on the right-hand side of Eq. ( <ref type="formula">44</ref>) stands for entropy generation due to heat transfer, while the second term stands for entropy generation due to fluid flow. The entropy generation rate N s , defined in Eq. ( <ref type="formula">45</ref>) for our flow, is a function of the cross-sectional coordinate &#563; and, thus, will vary across the cross-section. However, unlike the temperature and velocity distributions, but like the flow rate and the total energy, entropy can also be expressed as an extensive property. Thus, it is more insightful to study its behavior on an average basis, as opposed to studying its behavior as a field, i.e., a distribution, in &#563;. To this end, we define the average (dimensionless) entropy generation rate across the channel height:</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="2.6">Bejan number</head><p>The expression for entropy generation rate does not convey which of the two entropy generation mechanisms-fluid flow and heat transfer-dominates. Another dimensionless number, termed the Bejan number, can be defined to ascertain which mechanism of entropy generation is more significant <ref type="bibr">[46]</ref> (see also the discussion in <ref type="bibr">[47]</ref>). The Bejan number Be is the ratio of entropy generated due to heat transfer to the total entropy generated:</p><p>Notice that, just as N s in Eq. ( <ref type="formula">44</ref>), Be varies across the channel width, suggesting that the relative proportion of entropy generation due to heat transfer is different at different vertical locations in the channel.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="3">Results and discussion</head><p>The equations for momentum transfer, heat transfer and entropy generation have been derived, solved exactly or reduced to quadratures in Sec. 2. In this section, we would like to discuss the fluid mechanics, heat transfer, and thermodynamics of power-law fluids in heated microchannels with asymmetric slip for particular/illustrative values of the parameters, as tabulated in Table <ref type="table">1</ref>. In doing so, we present some novel aspects to the physics of this system. Note that we have kept Br &#8242; constant. The reason is that the effects of Br &#8242; on heat transfer and entropy generation characteristics of power-law fluid have already been addressed in detail by Tso et al. <ref type="bibr">[25]</ref> and Hung <ref type="bibr">[33]</ref>. The value of power-law index n has been taken to be either 0.5 or 1.5 to cover both the shear-thinning and shear-thickening aspects of non-Newtonian fluids. The dimensionless slip coefficient on upper wall is constant, K2 = 1, while the corresponding one on the lower wall, K1 , is given four different values. This is in agreement with the theme of the paper, which is to study the effect of such asymmetric slip on the posed thermofluids problem. We have also allowed asymmetry in imposed uniform heat fluxes on the channel walls through the ratio q 2 /q 1 . The results in the figures discussed below were generated by first solving numerically the non-linear algebraic Eq. ( <ref type="formula">26</ref>) for &#964;w1 given K1 , K2 = 1, n and m. Then, this value of &#964;w1 , together with Eqs. ( <ref type="formula">24</ref>) and ( <ref type="formula">25</ref>), fully specifies the velocity profile. The numerical solution is obtained using standard subroutines from SciPy <ref type="bibr">[48]</ref>. The dimensionless velocity profile thus obtained is used to determine the dimensionless temperature profile across the channel by solving Eq. ( <ref type="formula">32</ref>) numerically, after first evaluating &#947; via Eq. <ref type="bibr">(35)</ref>. To this end, we use the interleaved 4(5) Dormand-Prince pair explicit Runge-Kutta method, namely the scipy.integrate.ode function dopri5, with a relative error tolerance of 10 -3 . The Nusselt number is obtained by substituting the dimensionless mean temperature into Eq. ( <ref type="formula">39</ref>). The dimensionless velocity and temperature profiles are finally also substituted into Eqs. ( <ref type="formula">45</ref>) and <ref type="bibr">(46)</ref>, and numerical integration is used to obtain the average entropy generation rate N s and the Bejan number distribution Be( &#563;).  </p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="3.1">Velocity profile</head><p>Figure <ref type="figure">2</ref> shows the velocity profile across the channel, as determined by Eqs. ( <ref type="formula">24</ref>)- <ref type="bibr">(26)</ref>, for different values of the slip coefficient K1 . The velocity profiles for shear-thinning (n &lt; 1) and shear-thickening (n &gt; 1) fluids are shown by the dashed and solid curves in the plot, respectively. This convention is followed throughout this paper with the exception of Fig. <ref type="figure">3</ref>.</p><p>For the sake of comparison, the velocity profile of a Newtonian fluid satisfying no slip at the walls is also shown in gray.</p><p>The vertical location at which the velocity gradient changes sign, which is the point of zero shear stress in the channel, is denoted by a filled circle on each curve. As can be seen immediately from the graph, the presence of slip increases the maximum velocity of both shear-shinning and shear-thickening fluids. However, shear-thinning fluids (n &lt; 1) (dashed curves) exhibit significantly less steep velocity profiles than shear-thickening fluids (n &gt; 1) (solid curves). This observation can be explained by noting that shear-thinning fluids will support a smaller shear stress and, consequently by Eq. ( <ref type="formula">7</ref>), smaller velocity gradients.</p><p>We also see that, for a fixed value of n, the velocity profile and its gradient are both affected by the asymmetric slip coefficient's magnitude. This is a new result due to asymmetric slip because, as shown in <ref type="bibr">[35]</ref>, the velocity profile of a power-law fluid subject to symmetric slip will have the same slope for all values of the slip coefficient, which is also well known for Newtonian microflow <ref type="bibr">[49,</ref><ref type="bibr">Sect. 24.4]</ref>. Therefore, for symmetric slip boundary conditions, slip affects only the advection of momentum but not its diffusion. Specifically, if &#363;0 ( &#563;) is the solution for the velocity profile without slip, then  the velocity profile with symmetric slip can always be written as &#363;( &#563;) = &#363;0 ( &#563;) + &#251;, where &#251; is some constant. In such a symmetric slip flow, one could thus model the problem simply as a shear-driven Couette flow, i.e., as the flow in a channel with walls moving at some appropriate velocities, as done in <ref type="bibr">[34]</ref>.</p><p>However, for the case slip treated herein, slip affects both the diffusion and advection of fluid momentum. Thus, a flow with asymmetric slip cannot simply be modeled as a Couette flow with moving walls, which should also be clear from the derivation in Sect. 2.2, specifically the form of the solution given in Eq. <ref type="bibr">(24)</ref>. We also observe that the vertical location of the maximum velocity, &#563;0 &#8801; y 0 /H = &#964;w1 , depends on the relative values of the slip coefficients (as parametrized by K1 in the present work). But, &#964;w1 does not depend on the shear-thinning or shear-thickening aspect of the fluid, as made clear by the lack of n in Eq. <ref type="bibr">(26)</ref>. For the cases of equal slip coefficients (labeled as K1 = 1 in Fig. <ref type="figure">2</ref>), the velocity reaches a maximum at midheight of the channel, i.e., at &#563;0 = &#964;w1 = 1/2, as mentioned in the discussion following Eq. ( <ref type="formula">26</ref>). However, for the case of asymmetric slip, the location of the maximum is closer to the wall on which the slip is larger (the upper wall for blue and red curves and the lower wall for yellow curves). Additionally, the velocity gradients are larger near the wall on which K is smaller. To understand this aspect, note that slip reduces friction on the walls. Consequently, the shear stress (and the velocity gradient) will be smaller on the wall where the slip is larger. Thus, the point of maximum velocity (i.e., zero velocity gradient) must be closer to the wall with larger K.</p><p>To buttress the above point, in Fig. <ref type="figure">3</ref> we plot the shear stress at the walls &#964;w{1,2} (as solid and dashed curves, respectively) as a function of the power-law index n for different values of the slip coefficient K1 . Due to the choice of coordinate system, &#964;w is positive on the lower wall (solid curves) but negative on  the upper wall (dashed curves). Consequently, Fig. <ref type="figure">3</ref> shows that enhanced slip reduces the shear stress at the wall since &#964;w1 decreases with K1 . However, a decrease in &#964;w1 is accompanied by an increase in the (absolute value of the) shear stress at the upper wall, &#964;w2 , even though the slip coefficient at the upper wall is constant. This observation is explained by noting that &#964;w2 = &#964;w1 -1 (0 &lt; &#964;w1 &lt; 1), after making Eq. ( <ref type="formula">4</ref>) dimensionless, thus the two wall shear stresses are coupled.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="3.2">Temperature distribution</head><p>There are three modes of heat transfer in the problem that we posed in Sect. 1, namely: axial advection, vertical conduction, and viscous dissipation. Axial advection is represented by the term on the left-hand side of Eq. ( <ref type="formula">27</ref>), vertical conduction is represented by the first term on its right-hand side, while viscous dissipation is represented by the second term on the right-hand side of Eq. ( <ref type="formula">27</ref>). Consequently, the temperature distribution is intimately coupled to the velocity field through the axial advection and viscous dissipation terms. Clearly, the fluid flow problem needs to be solved prior to attacking the heat transfer (and entropy generation) problem. This ordering is also the reflected in the history of convection heat transfer research: the Blasius solution for the laminar hydrodynamic boundary layer <ref type="bibr">[50]</ref> preceded the Pohlhausen solution for the corresponding thermal boundary layer <ref type="bibr">[51]</ref> by thirteen years (see also the discussion in <ref type="bibr">[52]</ref>). Likewise, we solved the fluid mechanical problem in Sect. 2.2 and the temperature distribution was analyzed in Sect. 2.3. In this subsection, we first analyze the temperature profile across the channel height for different values of the slip coefficient K1 in Figs. <ref type="figure">4</ref> and<ref type="figure">5</ref>, for q 2 /q 1 = 0.5 and  ) Dimensionless temperature distribution &#952; across the height &#563; of the channel with a larger imposed heat flux at the upper wall (q 2 /q 1 = 2.0 &gt; 1), for different values of the slip coefficient K1 . The dashed curves show the profiles of a shear-thinning fluid with power-law exponent n = 0.5, while the solid curves show the profiles of a shearthickening fluid with n = 1.5.</p><p>q 2 /q 1 = 2.0, respectively. To highlight the physics studied herein, the temperature profile corresponding to a Newtonian fluid subject to no slip ( K1 = K2 = 0) and with equal applied heat fluxes (q 2 /q 1 = 1) on the walls is shown as a gray curve. Observe that, from Eq. ( <ref type="formula">28</ref>), &#952; = 0 at &#563; = 0 while the imposed wall heat flux is into the fluid, so the temperature the interior must be lower than that of wall "1," resulting in negative values of &#952; as depicted in Figs. <ref type="figure">4</ref> and<ref type="figure">5</ref>.</p><p>Next, we observe that the overall temperature distribution inside of the channel is damped out (becomes less negative) with increasing K1 . This nontrivial effect can be rationalized by noting that an increase in slip leads to an increase in the fluid velocity and a concomitant increase in the ability of the fluid to carry heat, resulting in higher temperatures. Thus, for a fixed heat flux ratio q 2 /q 1 , we see that the minimum of &#952; decreases with K1 . In both cases (q 2 /q 1 = 0.5 and q 2 /q 1 = 2.0), the vertical &#563;-location of the minimum (i.e., where &#8706;&#952;/&#8706; &#563; = 0) moves closer to the lower wall as the slip coefficient increases. Now, comparing Fig. <ref type="figure">4</ref> to Fig. <ref type="figure">5</ref>, we further understand that the location at which &#8706;&#952;/&#8706; &#563; = 0 is closer to the cooler wall (specifically, the upper wall in Fig. <ref type="figure">4</ref> and the lower wall in Fig. <ref type="figure">5</ref>), where the heat flux is smaller. This effect is attributed to the fact that a higher heat flux at the wall drives a higher temperature gradient into the fluid, owing to Fourier's law of heat conduction.</p><p>The final observation that we would like to make about Figs. <ref type="figure">4</ref> and<ref type="figure">5</ref> is that the effect of increasing the slip coefficient is more pronounced when the lower wall is hotter (i.e., q 2 /q 1 &lt; 1). This is because the two phenomena discussed above-higher heat flux and larger slip at the lower wall-now work in tandem to increase the temperature at the lower wall. Conceivably, this synergy between asymmetric slip and asym- Nu q 2 /q 1 = 0.5 K1 = 0.5 K1 = 0.75 K1 = 1 K1 = 1.25</p><p>Figure <ref type="figure">6</ref>: (Color online.) The Nusselt number along the lower wall ( &#563; = 0) for different values of the power-law exponent n and the slip coefficient K1 . The ratio of imposed heat fluxes is q 2 /q 1 = 0.5.</p><p>metric imposed heat flux could be exploited in microscale heat transfer applications.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="3.3">Nusselt number</head><p>Recall that the Nusselt number is the dimensionless heat transfer coefficient (HTC), as given by Eq. ( <ref type="formula">39</ref>), which is the ratio of the heat flux to the temperature difference between the fluid and the lower channel wall. Although a corollary of Newton's law of cooling, as discussed by Bejan <ref type="bibr">[53]</ref> the concept of a heat transfer coefficient is, in fact, inherently ambiguous. For example, in natural convection the heat transfer coefficient is necessarily a function of the temperature difference and is, thus, not constant <ref type="bibr">[45]</ref>. On the other hand, the widespread use of computational fluid dynamics (CFD), wherein the energy balance at the surface is enforced explicitly by mapping the temperatures or heat fluxes directly from one domain to another <ref type="bibr">[54]</ref>, has allowed for more general analyses of thermofluids problems, often obviating the need for the Nusselt number as a fundamental physical quantity. We also understand that the Nusselt number is completely defined only by specifying a reference temperature, see Eq. ( <ref type="formula">39</ref>), which itself depends on the rate of heat transfer-a quantity that we are trying to predict in the first place! This makes the definition of the Nusselt number a circular one. Nevertheless, for forced convection in unidirectional flows, as in the present study, the Nusselt number remains a relevant quantity that can be used to understand the thermal characteristics of heat transfer in the flow. Indeed, this has been the quantity of interest in a large number of scientific works on heat transfer in microchannel flows <ref type="bibr">[19,</ref><ref type="bibr">20,</ref><ref type="bibr">25,</ref><ref type="bibr">26,</ref><ref type="bibr">35,</ref><ref type="bibr">34]</ref>.</p><p>In the present work, we have imposed uniform heat fluxes (independent of the axial coordinate, x) on the channel walls. However, we have allowed the uniform heat flux on the lower wall, q 1 , to be different from the uniform heat flux on the up-  </p><p>per wall, q 2 . Consequently, Nu along the lower wall ( &#563; = 0) necessarily differs from Nu along the upper wall ( &#563; = 1). Still, Nu is independent of x. This result has been shown with due mathematical rigor by Tso et. al. <ref type="bibr">[25]</ref>. Thus, in Figs. <ref type="figure">6</ref> and<ref type="figure">7</ref>, we only plot the Nusselt number Nu along the lower wall as a function of the power-law index n of the fluid and for different values of the slip coefficient K1 . Specifically, Fig. <ref type="figure">6</ref> shows the Nu dependence on n for a heat flux ratio q 2 1 = 0.5, while Fig. <ref type="figure">7</ref> shows the Nu dependence on n for a heat flux ratio q 2 /q 1 = 2.0. From Figs. <ref type="figure">6</ref> and<ref type="figure">7</ref>, we immediately conclude that the Nusselt number increases with the amount slip. From our earlier discussion of the temperature profile: an increase in the wall slip increases the fluid's ability to advect heat near the walls, leading to enhanced heat transfer. On the other hand, Nu decreases with the power-law index n, consistent with previous studies <ref type="bibr">[34,</ref><ref type="bibr">35]</ref>. For small values of n, the shear-thinning aspect of the fluid is more prominent, reducing resistance to flow and increasing the velocity. Consequently, the flow's ability to transport heat is enhanced.</p><p>Finally, we see that Nu increases significantly with the ratio q 2 /q 1 (as can be obviously inferred by comparing the vertical axes scales between Figs. <ref type="figure">6</ref> and<ref type="figure">7</ref>). On one hand, this dependence is in stark contrast to the case of equal imposed heat fluxes (when q 2 /q 1 = 1), in which the Nusselt number is independent of the value of q 2 = q 1 <ref type="bibr">[35]</ref>. On the other hand, this dependence is consonant with previous studies with unequal imposed heat fluxes in which Nu depends on q 2 /q 1 <ref type="bibr">[25,</ref><ref type="bibr">26]</ref>. 2  This again suggests that such an enhancement of heat transfer due to asymmetric slip and asymmetric imposed heat fluxes could be exploited in the design of microscale heat transfer 2 As a consistency check, note that the Nusselt number for the special case of a Newtonian fluid subject to no slip and equal imposed heat fluxes was found to be 4.1176 based on our mathematical results, which agrees with the value reported in literature <ref type="bibr">[25]</ref> to four decimals.  The ratio of imposed heat fluxes is q 2 /q 1 = 0.5.</p><p>equipment.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="3.4">Average entropy generation</head><p>We have defined the average entropy generation rate N s in Eq. <ref type="bibr">(45)</ref>. In this subsection, the average entropy generation rate has been plotted as a function of the power-law index n of the fluid in Figs. <ref type="figure">8</ref> and<ref type="figure">9</ref> for q 2 /q 1 = 0.5 and q 2 /q 1 = 2.0, respectively. First, it is seen from Figs. 8 and 9 that N s increases with the power-law index n. This observation is attributed to the fact that an increase in n leads to higher velocity and temperature gradients inside the channel, as already explained in Sections 3.1 and 3.2. Consequently, more entropy is generated by both heat transfer and viscous friction.</p><p>Second, it is evident from Figs. 8 and 9 that N s decreases with the slip coefficient at the walls. As we have already seen in Sections 3.1 and 3.2, a larger slip leads to more thorough mixing and more uniform temperature and velocity distributions inside the flow. Thus, the inherent thermodynamic irreversibility of the flow (as measured by the entropy generation rate) is diminished as slip increases.</p><p>Lastly, N s increases with the ratio of imposed heat fluxes, q 2 /q 1 . This trend is expected because imposing larger heat fluxes leads to larger temperature gradients in the channel, and hence to further thermodynamic irreversibility.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="3.5">Bejan number</head><p>In thermal engineering, researchers concern themselves with more than just the amount of entropy generated. Their imperative is to make the system more efficient by minimizing the entropy generated inside it <ref type="bibr">[30]</ref>. To that end, they need to understand the various modes by which entropy is generated inside the physical system under investigation. The question  The ratio of imposed heat fluxes is q 2 /q 1 = 2.0.</p><p>"How is entropy minimized?" then begets the question "How is entropy generated?". Paoletti et al. <ref type="bibr">[46]</ref> defined the Bejan number to address this issue. The Bejan number Be is the ratio of the entropy generated due to heat transfer to the total entropy generated, as given in Eq. <ref type="bibr">(46)</ref>. It follows that an increase in fluid flow irreversibility (velocity gradients) causes the Bejan number to decrease, an increase in heat transfer irreversibility (temperature gradients) causes the Bejan number to increase. By this definition, it is obvious that for &#563; such that Be( &#563;) &gt; 1/2, the entropy generation is primarily due to heat transfer irreversibility, and conversely, fluid friction irreversibility dominates in the region(s) where Be( &#563;) &lt; 1/2. The two entropy generation mechanisms are of equal "importance" when/where Be = 1/2.</p><p>The distribution of the Bejan number Be( &#563;) across the channel width for different slip coefficientsis shown in Figs. 10 and 11 for q 2 /q 1 = 0.5 and q 2 /q 1 = 2.0, respectively. The global maximum (here, at Be = 1 for all cases shown) of each curve corresponds to the point at which the velocity gradient vanishes (&#8706; &#363;/&#8706; &#563; = 0), while the global minimum (here, at Be = 0 for all cases shown) corresponds to the point at which the temperature gradient vanishes (&#8706;&#952;/&#8706; &#563; = 0). For a flow with symmetric slip ( K1 = 1) and equal heat flux boundary conditions (q 2 /q 1 = 1), both the temperature and velocity gradients vanish exactly at the centerline ( &#563; = 1/2), making it a point of singularity for the Be profile <ref type="bibr">[35]</ref>. The vertical line Be = 1/2 denotes the line of demarcation for a trade-off in the relative importance of the two entropy generation mechanisms. We observe from both Figs. 10 and 11 that a particular trade-off point exists near the centerline of the channel (between the global maximum and the global minimum of Be heretofore described) for both shear-thinning and shear-thickening fluids and for all values of the slip coefficient, unlike the case of symmetric slip <ref type="bibr">[35]</ref>.</p><p>For the same value of q 2 /q 1 , i.e., restricting to either Fig. <ref type="figure">10</ref> 0.0 0.2 0.6 0.0 y q 2 /q 1 = 0.5 K1 = 0.5 K1 = 0.75 K1 = 1 K1 = 1.25 or Fig. <ref type="figure">11</ref>, it is seen that the global maximum of the Be curve shifts towards the lower wall when the slip coefficient on the lower wall, namely K1 , increases. This trend is explained by recalling the velocity profiles in Fig. <ref type="figure">2</ref>, in which the location of the maximum of the velocity profile shifts towards the lower wall as K1 increases.</p><p>In both Figs. 10 and 11, we see that the behavior of the Be curves is different at each wall. At the lower wall, the Bejan number is smaller for smaller slip, i.e., the blue curve (smaller K1 ) is to the left of the yellow curve (larger K1 ). However, the situation is reversed where the curves terminate on the upper wall. The spanwise location at which this reversal or "switch" occurs, i.e., the &#563; value at which the curves cross each other, is shown with a filled circle in each figure. This circle is closer to the cooler wall in each of Figs. 10 and 11. We understand from our discussion of the velocity distribution in Sect. 3.1 that as the slip coefficient K1 increases, the shear stress &#964;w1 on the lower wall decreases; this leads to an increase in Be near said wall. However, the reverse holds true at the upper wall, where an increase in K1 leads to a corresponding increase in &#964;w2 and a decrease in Be. The location at which this reversal occurs is closer to the cooler wall because the temperature gradients there are smaller, i.e., the relative influence of velocity gradients is more pronounced.</p><p>We also see that, overall, Be( &#563;; n &lt; 1) &gt; Be( &#563;; n &gt; 1), i.e., the Bejan number for shear-thinning fluids is higher than that for shear-thickening fluids, in most parts of the microchannel. To explain this observation, note that shear-thinning fluids exhibit smaller velocity gradients compared to shear-thickening fluids (i.e., less resistance to flow), which translates means that a larger portion of the entropy generation is due to heat transfer.</p><p>Next, we observe that in Figs.  (local) maximum in the Be( &#563;) profile near the cooler wall for shear-thinning fluids for all values of slip coefficients (and also for shear-thickening fluids with K1 &lt; 1). This second (local) maximum is absent in the case of symmetric slip <ref type="bibr">[35]</ref>. To understand this observation, note that the velocity gradients in a shear-thinning fluid quickly diminish away from the walls, while the temperature gradients do not drop-off (recall the discussion in Sects. 3.1 and 3.2). This discrepancy in how fast velocity and temperature gradients are dissipated in this microflow leads to the presence of the local maximum in the Be profile. Finally, we note that some of the curves corresponding to shear-thinning fluids with K1 &gt; 1 in Fig. <ref type="figure">10</ref>, and all the curves in Fig. <ref type="figure">11</ref>, cross the vertical line Be = 1/2 twice: near the channel centerline (as discussed previously) and again close to the cooler wall. <ref type="foot">3</ref> Thus the trade-off between the relative importance of the two entropy generation mechanisms happens at two locations for these specific flows. This novel effect also appears to be entirely due to asymmetric slip. Evidently, non-Newtonian rheology, asymmetric slip and asymmetric imposed heat fluxes can be used to tune how entropy is generated across the channel in a microflow.</p></div>
<div xmlns="http://www.tei-c.org/ns/1.0"><head n="4">Conclusion</head><p>We studied the effect of asymmetric slip on the hydrodynamics, heat transfer and entropy generation of a thermally developed flow of a non-Newtonian fluid in a microchannel subject to asymmetric nonlinear slip and unequal heat fluxes at the walls. Under a power-law rheological model, the governing equations were specialized to viscous unidirectional flow, yielding an exact but implicit solution for the velocity profile. The heat transfer and entropy generation characteristics (specifically, Nusselt number, average entropy generation rate and Bejan number) were reduced quadratures.</p><p>In summary, we have established the following. First, slip reduces the shear stress acting on the channel walls, especially at the wall with "larger" slip. Second, slip promotes uniformity in the temperature field. The temperature in the fluid increases with slip asymmetry, in particular because of its enhanced capacity to transfer heat by advection. Third, flows with larger slip induce less entropy generation, specifically the Bejan number Be is larger near the hotter wall in the case of unequal imposed heat fluxes. Overall, slip reduces both heat transfer irreversibility and fluid flow irreversibility, however, it has a more pronounced effect on fluid flow irreversibility by directly influencing the velocity profile. Unlike the case of symmetric slip, we found that, for certain combinations of the power-law index n, the dimensionless slip asymmetry parameter K1 , and the imposed heat flux asymmetry q 2 /q 1 at the channel walls, a second trade-off point between the entropy generation mechanisms exists, apart from the trade-off point closer to the channel's centerline.</p><p>We believe that our theoretical analysis will be useful in thermal engineering. Specifically, our conclusions could be used to tailor heat transfer in microchannel flows of complex fluids (such as blood or dense polymeric suspensions) to minimize thermal irreversibility, for example, by tuning the channel's surface properties so that the complex fluid's flow exhibits asymmetric slip. Likewise, in the case of unequal boundary heat fluxes, imposing the higher flux on the wall with larger slip leads to enhanced heat transfer into the fluid.</p><p>In future work, heat transfer and entropy generation in the asymmetric slip microflows of gases could be attacked along on the lines of <ref type="bibr">[55,</ref><ref type="bibr">56,</ref><ref type="bibr">57]</ref>. In such flows, a temperature jump boundary condition emerges at the boundaries, as originally discussed by Smoluchowski <ref type="bibr">[58]</ref>. However, as noted in <ref type="bibr">[5]</ref>, it is currently an open question whether the temperature jump boundary conditions derived for slip flow of gasses can apply to complex liquids (such as the example dense suspension, e.g., <ref type="bibr">[38,</ref><ref type="bibr">39]</ref>, considered in this work). </p></div><note xmlns="http://www.tei-c.org/ns/1.0" place="foot" n="3" xml:id="foot_0"><p>To be precise, however, we also note that, in Fig.10, some of the shearthickening curves with K &lt; 1 appear to approach Be = 1/2 again near the hotter wall, suggesting a highly nontrivial dependence on the model parameters.</p></note>
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