More Like this

1. Atypical Perception of Sounds in Minimally and Low Verbal Children and Adolescents With Autism as Revealed by Behavioral and Neural Measures

   https://doi.org/10.1002/aur.2363  

   Schwartz, Sophie ; Wang, Le ; Shinn‐Cunningham, Barbara G. ; Tager‐Flusberg, Helen ( September 2020 , Autism Research)

   The common display of atypical behavioral responses to sounds by individuals with autism (ASD) suggests that they process sounds differently. Within ASD, individuals who are minimally or low verbal (ASD‐MLV) are suspected to have greater auditory processing impairments. However, it is unknown whether atypical auditory behaviors are related to receptive language and/or neural processing of sounds in ASD‐MLV. In Experiment 1, we compared the percentage of time 47 ASD‐MLV and 36 verbally fluent (ASD‐V) participants, aged 5–21, displayed atypical auditory or visual sensory behaviors during the administration of the Autism Diagnostic Observation Schedule (ADOS). In Experiment 2, we tested whether atypical auditory behaviors were more frequent in ASD‐MLV participants with receptive language deficits. In Experiment 3, we tested whether atypical auditory behaviors correlated with neural indices of sensitivity to perceptual sound differences as measured by the amplitude of neural responses to nonspeech intensity deviants. We found that ASD‐MLV participants engaged in atypical auditory behaviors more often than ASD‐V participants; in contrast, the incidence of atypical visual behaviors did not differ between the groups. Lower receptive language skills in the ASD‐MLV group were predicted by greater incidence of atypical auditory behaviors. Exploratory analyses revealed a significant negative correlation between the amount of atypical auditory behaviors and the amplitude of neural response to deviants. Future work is needed to elucidate whether the relationship between atypical auditory behaviors and receptive language impairments in ASD‐MLV individuals results from disruptions in the brain mechanisms involved in auditory processing.

   Minimally and low verbal children and adolescents with autism (ASD‐MLV) displayed more atypical auditory behaviors (e.g., ear covering and humming) than verbally fluent participants with ASD. In ASD‐MLV participants, time spent exhibiting such behaviors was associated with receptive vocabulary deficits and weaker neural responses to changes in sound loudness. Findings suggest that individuals with ASD with both severe expressive and receptive language impairments process sounds differently.Autism Res2020, 13: 1718–1729. © 2020 International Society for Autism Research and Wiley Periodicals LLC

    

   more » « less
2. Mechanisms of voice control related to prosody in autism spectrum disorder and first‐degree relatives

   https://doi.org/10.1002/aur.2156  

   Patel, Shivani P. ; Kim, Jason H. ; Larson, Charles R. ; Losh, Molly ( June 2019 , Autism Research)

   Differences in prosody (e.g., intonation, rhythm) are among the most obvious language‐related impairments in autism spectrum disorder (ASD), and significantly impact communication. Subtle prosodic differences have also been identified in a subset of clinically unaffected first‐degree relatives of individuals with ASD, and may reflect genetic liability to ASD. This study investigated the neural basis of prosodic differences in ASD and first‐degree relatives through analysis of feedforward and feedback control involved in the planning, production, self‐monitoring, and self‐correction of speech by using a pitch‐perturbed auditory feedback paradigm during sustained vowel and speech production. Results revealed larger vocal response magnitudes to pitch‐perturbed auditory feedback across tasks in ASD and ASD parent groups, with differences in sustained vowel production driven by parents who displayed subclinical personality and language features associated with ASD (i.e., broad autism phenotype). Both ASD and ASD parent groups exhibited increased response onset latencies during sustained vowel production, while the ASD parent group exhibited decreased response onset latencies during speech production. Vocal response magnitudes across tasks were associated with prosodic atypicalities in both individuals with ASD and their parents. Exploratory event‐related potential (ERP) analyses in a subgroup of participants during the sustained vowel task revealed reduced P1 ERP amplitudes in the ASD group, with similar trends observed in parents. Overall, results suggest underdeveloped feedforward systems and neural attenuation in detecting audio‐vocal feedback may contribute to ASD‐related prosodic atypicalities. Importantly, results implicate atypical audio‐vocal integration as a marker of genetic risk to ASD, evident in ASD and among clinically unaffected relatives.Autism Res2019, 12: 1192–1210. © 2019 The Authors.Autism Research published by International Society for Autism Researchpublished by Wiley Periodicals, Inc.

   Previous research has identified atypicalities in prosody (e.g., intonation) in individuals with ASD and a subset of their first‐degree relatives. In order to better understand the mechanisms underlying prosodic differences in ASD, this study examined how individuals with ASD and their parents responded to unexpected differences in what they heard themselves say to modify control of their voice (i.e., audio‐vocal integration). Results suggest that disruptions to audio‐vocal integration in individuals with ASD contribute to ASD‐related prosodic atypicalities, and the more subtle differences observed in parents could reflect underlying genetic liability to ASD.

    

   more » « less
3. Individuals with autism spectrum disorder are impaired in absolute but not relative pitch and duration matching in speech and song imitation

   https://doi.org/10.1002/aur.2569  

   Wang, Li ; Pfordresher, Peter Q. ; Jiang, Cunmei ; Liu, Fang ( July 2021 , Autism Research)

   Individuals with autism spectrum disorder (ASD) often exhibit atypical imitation. However, few studies have identified clear quantitative characteristics of vocal imitation in ASD. This study investigated imitation of speech and song in English‐speaking individuals with and without ASD and its modulation by age. Participants consisted of 25 autistic children and 19 autistic adults, who were compared to 25 children and 19 adults with typical development matched on age, gender, musical training, and cognitive abilities. The task required participants to imitate speech and song stimuli with varying pitch and duration patterns. Acoustic analyses of the imitation performance suggested that individuals with ASD were worse than controls on absolute pitch and duration matching for both speech and song imitation, although they performed as well as controls on relative pitch and duration matching. Furthermore, the two groups produced similar numbers of pitch contour, pitch interval‐, and time errors. Across both groups, sung pitch was imitated more accurately than spoken pitch, whereas spoken duration was imitated more accurately than sung duration. Children imitated spoken pitch more accurately than adults when it came to speech stimuli, whereas age showed no significant relationship to song imitation. These results reveal a vocal imitation deficit across speech and music domains in ASD that is specific to absolute pitch and duration matching. This finding provides evidence for shared mechanisms between speech and song imitation, which involves independent implementation of relative versus absolute features.

   Individuals with autism spectrum disorder (ASD) often exhibit atypical imitation of actions and gestures. Characteristics of vocal imitation in ASD remain unclear. By comparing speech and song imitation, this study shows that individuals with ASD have a vocal imitative deficit that is specific to absolute pitch and duration matching, while performing as well as controls on relative pitch and duration matching, across speech and music domains.

    

   more » « less
4. Metaphor processing in autism: A systematic review and meta-analysis

   Morsanyi, K. ; Stamenković, D. ; Holyoak, K. J. ( September 2020 , Developmental review)

   null (Ed.)

   Impairments related to figurative language understanding have been considered to be one of the diagnostic and defining features of autism. Metaphor comprehension and production in autism spectrum disorder (ASD) as compared to typically developing (TD) individuals have been investigated for around thirty years, generally showing an overall advantage for TD groups. We present a preregistered systematic review and meta-analysis including a total of 15 studies that fulfilled our set of inclusion criteria (notably, ASD and TD groups matched in chronological age and verbal- or full-scale IQ). Along with accuracy, we also analyzed group differences in reaction time in the studies that reported them. The results revealed a medium-to-large group difference favoring TD over ASD groups based on accuracy measures, as well as a similar overall advantage for TD groups based on reaction times. There was reliable heterogeneity in effect sizes for group differences in accuracy, which was mostly explained by the effect of verbal intelligence, with differences in metaphor processing being smaller for participants with better verbal skills. Some of the variation in effect sizes may also be attributed to differences in types of metaphor processing tasks. We also evaluated the quality of the studies included in the meta-analysis, and the evidence relating to the potential presence of publication bias. 

   more » « less
5. Data‐Driven Learning for Pronunciation: Perception and Production of Lexical Stress and Prominence in Academic English

   https://doi.org/10.1002/tesq.3302  

   Hirschi, Kevin ; Kang, Okim ( January 2024 , TESOL Quarterly)

   Issues of intelligibility may arise amongst English learners when acquiring new words and phrases in North American academic settings, perhaps in part due to limited linguistic data available to the learner for understanding language use patterns. To this end, this paper examines the effects of Data‐Driven Learning for Pronunciation (DDLfP) on lexical stress and prominence in the US academic context. 65 L2 English learners in North American universities completed a diagnostic and pretest with listening and speaking items before completing four online lessons and a posttest on academic words and formulas (i.e., multi‐word sequences). Experimental group participants (n = 40) practiced using an audio corpus of highly proficient L2 speakers while comparison group participants (n = 25) were given teacher‐created pronunciation materials. Logistic regression results indicated that the group who used the corpus significantly increased their recognition of prominence in academic formulas. In the spoken tasks, both groups improved in their lexical stress pronunciation, but only the DDLfP learners improved their production of prominence in academic formulas. Learners reported that they valued DDLfP efforts for pronunciation learning across contexts and speakers. Findings have implications for teachers of L2 pronunciation and support the use of corpora for language teaching and learning.

    

   more » « less