Facile reduction of aryl halides with a combination of 5% Pd/C, B2(OH)4, and 4‐methylmorpholine is reported. Aryl bromides, iodides, and chlorides were efficiently reduced. Aryl dihalides containing two different halogen atoms underwent selective reduction: I over Br and Cl, and Br over Cl. Beyond these, aryl triflates were efficiently reduced. This combination was broadly general, effectuating reductions of benzylic halides and ethers, alkenes, alkynes, aldehydes, and azides, as well as for
The design of catalysts for asymmetric propargylations remains a challenging task, with only a handful of methods providing access to enantioenriched homopropargylic alcohols. In this work, guided by previously reported computational predictions, a set of atropisomeric bipyridine
- Award ID(s):
- 1665407
- NSF-PAR ID:
- 10255155
- Publisher / Repository:
- Wiley Blackwell (John Wiley & Sons)
- Date Published:
- Journal Name:
- Advanced Synthesis & Catalysis
- Volume:
- 362
- Issue:
- 23
- ISSN:
- 1615-4150
- Page Range / eLocation ID:
- p. 5467-5474
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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