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1. Locating trauma centers considering patient safety

   https://doi.org/10.1007/s10729-021-09576-y  

   Hirpara, Sagarkumar; Vaishnav, Monit; Parikh, Pratik J.; Kong, Nan; Parikh, Priti (June 2022, Health Care Management Science)
2. The association between latent trauma and brain structure in children

   https://doi.org/10.1038/s41398-021-01357-z  

   Jeong, Hee Jung; Durham, E. Leighton; Moore, Tyler M.; Dupont, Randolph M.; McDowell, Malerie; Cardenas-Iniguez, Carlos; Micciche, Emily T.; Berman, Marc G.; Lahey, Benjamin B.; Kaczkurkin, Antonia N. (June 2021, Translational Psychiatry)

   null (Ed.)

   Abstract The developing brain is marked by high plasticity, which can lead to vulnerability to early life stressors. Previous studies indicate that childhood maltreatment is associated with structural aberrations across a number of brain regions. However, prior work is limited by small sample sizes, heterogeneous age groups, the examination of one structure in isolation, the confounding of different types of early life stressors, and not accounting for socioeconomic status. These limitations may contribute to high variability across studies. The present study aimed to investigate how trauma is specifically associated with cortical thickness and gray matter volume (GMV) differences by leveraging a large sample of children ( N  = 9270) from the Adolescent Brain Cognitive Development SM Study (ABCD Study ® ). A latent measure of trauma exposure was derived from DSM-5 traumatic events, and we related this measure of trauma to the brain using structural equation modeling. Trauma exposure was associated with thinner cortices in the bilateral superior frontal gyri and right caudal middle frontal gyrus ( p fdr - values < .001) as well as thicker cortices in the left isthmus cingulate and posterior cingulate ( p fdr - values ≤ .027), after controlling age, sex, and race/ethnicity. Furthermore, trauma exposure was associated with smaller GMV in the right amygdala and right putamen ( p fdr - values ≤ .048). Sensitivity analyses that controlled for income and parental education were largely consistent with the main findings for cortical thickness. These results suggest that trauma may be an important risk factor for structural aberrations, specifically for cortical thickness differences in frontal and cingulate regions in children. 

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3. Speech-Based Activity Recognition for Trauma Resuscitation

   https://doi.org/10.1109/ICHI48887.2020.9374372  

   Abdulbaqi, Jalal; Gu, Yue; Xu, Zhichao; Gao, Chenyang; Marsic, Ivan; Burd, Randall S. (November 2020, 2020 IEEE International Conference on Healthcare Informatics (ICHI))

   null (Ed.)
4. Trauma as Displacement: Observations from Refugee Resettlement

   https://doi.org/10.1080/24694452.2021.1956296  

   Ehrkamp, Patricia; Loyd, Jenna M.; Secor, Anna J. (April 2022, Annals of the American Association of Geographers)
5. Gut mycobiome dysbiosis after sepsis and trauma

   https://doi.org/10.1186/s13054-023-04780-4  

   Park, Gwoncheol; Munley, Jennifer A; Kelly, Lauren S; Kannan, Kolenkode B; Mankowski, Robert T; Sharma, Ashish; Upchurch, Gilbert; Casadesus, Gemma; Chakrabarty, Paramita; Wallet, Shannon M; et al (December 2024, Critical Care)

   Abstract BackgroundSepsis and trauma are known to disrupt gut bacterial microbiome communities, but the impacts and perturbations in the fungal (mycobiome) community after severe infection or injury, particularly in patients experiencing chronic critical illness (CCI), remain unstudied. MethodsWe assess persistence of the gut mycobiome perturbation (dysbiosis) in patients experiencing CCI following sepsis or trauma for up to two-to-three weeks after intensive care unit hospitalization. ResultsWe show that the dysbiotic mycobiome arrays shift toward a pathobiome state, which is more susceptible to infection, in CCI patients compared to age-matched healthy subjects. The fungal community in CCI patients is largely dominated byCandidaspp; while, the commensal fungal species are depleted. Additionally, these myco-pathobiome arrays correlate with alterations in micro-ecological niche involving specific gut bacteria and gut-blood metabolites. ConclusionsThe findings reveal the persistence of mycobiome dysbiosis in both sepsis and trauma settings, even up to two weeks post-sepsis and trauma, highlighting the need to assess and address the increased risk of fungal infections in CCI patients. Graphical Abstract 

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