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1. GHz Ultrasonic Chip-Scale Device Induces Ion Channel Stimulation in Human Neural Cells

   https://doi.org/10.1038/s41598-020-58133-0  

   Balasubramanian, Priya S. ; Singh, Ankur ; Xu, Chris ; Lal, Amit ( February 2020 , Scientific Reports)

   Emergent trends in the device development for neural prosthetics have focused on establishing stimulus localization, improving longevity through immune compatibility, reducing energy re-quirements, and embedding active control in the devices. Ultrasound stimulation can single-handedly address several of these challenges. Ultrasonic stimulus of neurons has been studied extensively from 100 kHz to 10 MHz, with high penetration but less localization. In this paper, a chip-scale device consisting of piezoelectric Aluminum Nitride ultrasonic transducers was engineered to deliver gigahertz (GHz) ultrasonic stimulus to the human neural cells. These devices provide a path towards complementary metal oxide semiconductor (CMOS) integration towards fully controllable neural devices. At GHz frequencies, ultrasonic wavelengths in water are a few microns and have an absorption depth of 10–20 µm. This confinement of energy can be used to control stimulation volume within a single neuron. This paper is the first proof-of-concept study to demonstrate that GHz ultrasound can stimulate neuronsin vitro. By utilizing optical calcium imaging, which records calcium ion flux indicating occurrence of an action potential, this paper demonstrates that an application of a nontoxic dosage of GHz ultrasonic waves$$(\ge 0.05\frac{W}{c{m}^{2}})$$$\left(\ge 0.05\frac{W}{c{m}^2}\right)$caused an average normalized fluorescence intensity recordings >1.40 for the calcium transients. Electrical effects due to chip-scale ultrasound delivery was discounted as the sole mechanism in stimulation, with effects tested atα = 0.01 statistical significance amongst all intensities and con-trol groups. Ionic transients recorded optically were confirmed to be mediated by ion channels and experimental data suggests an insignificant thermal contributions to stimulation, with a predicted increase of 0.03^oCfor$$1.2\frac{W}{c{m}^{2}}\cdot $$$1.2\frac{W}{c{m}^2}\cdot$This paper paves the experimental framework to further explore chip-scale axon and neuron specific neural stimulation, with future applications in neural prosthetics, chip scale neural engineering, and extensions to different tissue and cell types.

    

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2. Plasmonically enhanced mid-IR light source based on tunable spectrally and directionally selective thermal emission from nanopatterned graphene

   https://doi.org/10.1038/s41598-020-73582-3  

   Shabbir, Muhammad Waqas ; Leuenberger, Michael N. ( October 2020 , Scientific Reports)

   We present a proof of concept for a spectrally selective thermal mid-IR source based on nanopatterned graphene (NPG) with a typical mobility of CVD-grown graphene (up to 3000$$\hbox {cm}^2\,\hbox {V}^{-1}\,\hbox {s}^{-1}$$${\text{cm}}^2{\text{V}}^{-1}{\text{s}}^{-1}$), ensuring scalability to large areas. For that, we solve the electrostatic problem of a conducting hyperboloid with an elliptical wormhole in the presence of anin-planeelectric field. The localized surface plasmons (LSPs) on the NPG sheet, partially hybridized with graphene phonons and surface phonons of the neighboring materials, allow for the control and tuning of the thermal emission spectrum in the wavelength regime from$$\lambda =3$$$\lambda =3$to 12$$\upmu$$$\mu$m by adjusting the size of and distance between the circular holes in a hexagonal or square lattice structure. Most importantly, the LSPs along with an optical cavity increase the emittance of graphene from about 2.3% for pristine graphene to 80% for NPG, thereby outperforming state-of-the-art pristine graphene light sources operating in the near-infrared by at least a factor of 100. According to our COMSOL calculations, a maximum emission power per area of$$11\times 10^3$$$11\times {10}^3$W/$$\hbox {m}^2$$${\text{m}}^2$at$$T=2000$$$T=2000$K for a bias voltage of$$V=23$$$V=23$V is achieved by controlling the temperature of the hot electrons through the Joule heating. By generalizing Planck’s theory to any grey body and deriving the completely general nonlocal fluctuation-dissipation theorem with nonlocal response of surface plasmons in the random phase approximation, we show that the coherence length of the graphene plasmons and the thermally emitted photons can be as large as 13$$\upmu$$$\mu$m and 150$$\upmu$$$\mu$m, respectively, providing the opportunity to create phased arrays made of nanoantennas represented by the holes in NPG. The spatial phase variation of the coherence allows for beamsteering of the thermal emission in the range between$$12^\circ$$${12}^{\circ }$and$$80^\circ$$${80}^{\circ }$by tuning the Fermi energy between$$E_F=1.0$$$E_F=1.0$eV and$$E_F=0.25$$$E_F=0.25$eV through the gate voltage. Our analysis of the nonlocal hydrodynamic response leads to the conjecture that the diffusion length and viscosity in graphene are frequency-dependent. Using finite-difference time domain calculations, coupled mode theory, and RPA, we develop the model of a mid-IR light source based on NPG, which will pave the way to graphene-based optical mid-IR communication, mid-IR color displays, mid-IR spectroscopy, and virus detection.

    

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3. Electrically tunable total reflection of light by oblique helicoidal cholesteric

   https://doi.org/10.1557/s43577-024-00723-8  

   Iadlovska, Olena_S ; Thapa, Kamal ; Rajabi, Mojtaba ; Mrukiewicz, Mateusz ; Shiyanovskii, Sergij_V ; Lavrentovich, Oleg_D ( June 2024 , MRS Bulletin)

   An oblique helicoidal state of a cholesteric liquid crystal (Ch_OH) is capable of continuous change of the pitch$$P$$$P$in response to an applied electric field. Such a structure reflects 50% of the unpolarized light incident along the Ch_OHaxis in the electrically tunable band determined by$$P$$$P$/2. Here, we demonstrate that at an oblique incidence of light, Ch_OHreflects 100% of light of any polarization. This singlet band of total reflection is associated with the full pitch$$P$$$P$. We also describe the satellite$$P/2$$$P/2$,$$P/3$$$P/3$, and$$P/4$$$P/4$bands. The$$P/2$$$P/2$and$$P/4$$$P/4$bands are triplets, whereas$$P/3$$$P/3$band is a singlet caused by multiple scatterings at$$P$$$P$and$$P/2$$$P/2$. A single Ch_OHcell acted upon by an electric field tunes all these bands in a very broad spectral range, from ultraviolet to infrared and beyond, thus representing a structural color device with enormous potential for optical and photonic applications.

   Pigments, inks, and dyes produce colors by partially consuming the energy of light. In contrast, structural colors caused by interference and diffraction of light scattered at submicrometer length scales do not involve energy losses, which explains their widespread in Nature and the interest of researchers to develop mimicking materials. The grand challenge is to produce materials in which the structural colors could be dynamically tuned. Among the oldest known materials producing structural colors are cholesteric liquid crystals. Light causes coloration by selective Bragg reflection at the periodic helicoidal structure formed by cholesteric molecules. The cholesteric pitch and thus the color can be altered by chemical composition or by temperature, but, unfortunately, dynamic tuning by electromagnetic field has been elusive. Here, we demonstrate that a cholesteric material in a new oblique helicoidal Ch_OHstate could produce total reflection of an obliquely incident light of any polarization. The material reflects 100% of light within a band that is continuously tunable by the electric field through the entire visible spectrum while preserving its maximum efficiency. Broad electric tunability of total reflection makes the Ch_OHmaterial suitable for applications in energy-saving smart windows, transparent displays, communications, lasers, multispectral imaging, and virtual and augmented reality.

    

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4. Molecular polariton electroabsorption

   https://doi.org/10.1038/s41467-022-35589-4  

   Cheng, Chiao-Yu ; Krainova, Nina ; Brigeman, Alyssa N. ; Khanna, Ajay ; Shedge, Sapana ; Isborn, Christine ; Yuen-Zhou, Joel ; Giebink, Noel C. ( December 2022 , Nature Communications)

   We investigate electroabsorption (EA) in organic semiconductor microcavities to understand whether strong light-matter coupling non-trivially alters their nonlinear optical [$${\chi }^{(3)}\left(\omega,{{{{\mathrm{0,0}}}}}\right)$$${\chi }^{\left(3\right)}\left(\omega ,\mathrm{0,\; 0}\right)$] response. Focusing on strongly-absorbing squaraine (SQ) molecules dispersed in a wide-gap host matrix, we find that classical transfer matrix modeling accurately captures the EA response of low concentration SQ microcavities with a vacuum Rabi splitting of$$\hslash \Omega \approx 200$$$\hslash \Omega \approx 200$meV, but fails for high concentration cavities with$$\hslash \Omega \approx 420$$$\hslash \Omega \approx 420$meV. Rather than new physics in the ultrastrong coupling regime, however, we attribute the discrepancy at high SQ concentration to a nearly dark H-aggregate state below the SQ exciton transition, which goes undetected in the optical constant dispersion on which the transfer matrix model is based, but nonetheless interacts with and enhances the EA response of the lower polariton mode. These results indicate that strong coupling can be used to manipulate EA (and presumably other optical nonlinearities) from organic microcavities by controlling the energy of polariton modes relative to other states in the system, but it does not alter the intrinsic optical nonlinearity of the organic semiconductor inside the cavity.

    

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5. Perfectly Packing a Square by Squares of Nearly Harmonic Sidelength

   https://doi.org/10.1007/s00454-023-00523-y  

   Tao, Terence ( July 2023 , Discrete & Computational Geometry)

   A well-known open problem of Meir and Moser asks if the squares of sidelength 1/nfor$$n\ge 2$$$n\ge 2$can be packed perfectly into a rectangle of area$$\sum _{n=2}^\infty n^{-2}=\pi ^2/6-1$$${\sum }_{n=2}^{\infty }{n}^{-2}={\pi }^2/6-1$. In this paper we show that for any$$1/2$1/2<t<1$, and any$$n_0$$$n_0$that is sufficiently large depending on t, the squares of sidelength$$n^{-t}$$$n^{-t}$for$$n\ge n_0$$$n\ge n_0$can be packed perfectly into a square of area$$\sum _{n=n_0}^\infty n^{-2t}$$${\sum }_{n=n_0}^{\infty }{n}^{-2t}$. This was previously known (if one packs a rectangle instead of a square) for$$1/2$1/2<t\le 2/3$(in which case one can take$$n_0=1$$$n_0=1$).

    

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