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Title: CHIASM, the human brain albinism and achiasma MRI dataset
Abstract We describe a collection of T1-, diffusion- and functional T2*-weighted magnetic resonance imaging data from human individuals with albinism and achiasma. This repository can be used as a test-bed to develop and validate tractography methods like diffusion-signal modeling and fiber tracking as well as to investigate the properties of the human visual system in individuals with congenital abnormalities. The MRI data is provided together with tools and files allowing for its preprocessing and analysis, along with the data derivatives such as manually curated masks and regions of interest for performing tractography.  more » « less
Award ID(s):
1912270 2203524 2148729 1734853 1636893
Author(s) / Creator(s):
; ; ; ; ; ; ; ; ; ;
Date Published:
Journal Name:
Scientific Data
Medium: X
Sponsoring Org:
National Science Foundation
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    To evaluate changes in fetal brain structural connectivity between 23 and 35 weeks postconceptional age using a spatiotemporal atlas of diffusion tensor imaging (DTI).

    Study Type



    Publicly available diffusion atlases, based on 60 healthy women (age 18–45 years) with normal prenatal care, from 23 and 35 weeks of gestation.

    Field Strength/Sequence

    3.0 Tesla/DTI acquired with diffusion‐weighted echo planar imaging (EPI).


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    Statistical Tests

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    Data Conclusion

    Extensive network development and refinement occur in the second and third trimesters, marked by a rapid increase in global integration and local segregation.

    Level of Evidence


    Technical Efficacy

    Stage 2

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