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Title: Measurement of Post-Exercise Response of Local Arterial Parameters Using an Adjustable Microfluidic Tactile Sensor
In this work, we demonstrate an adjustable microfluidic tactile sensor for measurement of post-exercise response of local arterial parameters. The sensor entailed a polydimethylsiloxane (PDMS) microstructure embedded with a 5×1 resistive transducer array. The pulse signal in an artery deflected the microstructure and registered as a resistance change by the transducer aligned at the artery. PDMS layers of different thicknesses were added to adjust the microstructure thickness for achieving good sensor-artery conformity at the radial artery (RA) and the carotid artery (CA). Pulse signals of nine (n=9) young healthy male subjects were measured at-rest and at different times post-exercise, and a medical instrument was used to simultaneously measure their blood pressure and heart rate. Vibration-model-based analysis was conducted on a measured pulse signal to estimate local arterial parameters: elasticity, viscosity, and radius. The arterial elasticity and viscosity increased, and the arterial radius decreased at the two arteries 1min post-exercise, relative to at-rest. The changes in pulse pressure (PP) and mean blood pressure (MAP) between at-rest and 1min post-exercise were not correlated with that of heart rate and arterial parameters. After the large 1min post-exercise response, the arterial parameters and PP all went back to their at-rest values over time post-exercise.Clinical Relevance— The study results show the potential application of an affordable, user-friendly device for a more comprehensive arterial health assessment.  more » « less
Award ID(s):
1936005
NSF-PAR ID:
10330070
Author(s) / Creator(s):
; ; ;
Date Published:
Journal Name:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society
ISSN:
2375-7477
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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