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1. Silver halide complexes of a borane/bis(phosphine) ligand

   https://doi.org/10.1039/c9dt02100k  

   Cao, Yihan; Shih, Wei-Chun; Bhuvanesh, Nattamai; Ozerov, Oleg V. (July 2019, Dalton Transactions)

   Silver halide complexes of a borane/bis(phosphine) ligand have been prepared and characterized. With AgF, the borane abstracts fluoride, resulting in a zwitterionic complex. With AgCl, AgBr, and AgI, the halide stays coordinated to Ag, with little to no Ag–B interaction. 

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2. Iridium Complexes of a Bis( N -pyrrolyl)boryl/Bis(phosphine) PBP Pincer Ligand

   https://doi.org/10.1021/acs.inorgchem.4c03554  

   Lee, Samuel_R; Bhuvanesh, Nattamai; Ozerov, Oleg_V (December 2024, Inorganic Chemistry)
3. Dimeric Rh Complexes Supported by a Bridging Phosphido/Bis(Phosphine) PPP Ligand

   https://doi.org/10.1021/acs.organomet.3c00492  

   Cosio, Mario N.; Lee, Samuel R.; Lai, Qingheng; Bhuvanesh, Nattamai; Zhou, Jia; Ozerov, Oleg V. (April 2024, Organometallics)
4. Mechanistic Investigations of the Asymmetric Hydrogenation of Enamides with Neutral Bis(phosphine) Cobalt Precatalysts

   https://doi.org/10.1021/jacs.2c06454  

   Mendelsohn, Lauren N.; Pavlovic, Ljiljana; Zhong, Hongyu; Friedfeld, Max R.; Shevlin, Michael; Hopmann, Kathrin H.; Chirik, Paul J. (July 2022, Journal of the American Chemical Society)
5. Cationic Bis(phosphine) Cobalt(I) Arene Complexes as Precatalysts for the Asymmetric Synthesis of Sitagliptin

   https://doi.org/10.1021/acscatal.2c01059  

   MacNeil, Connor S.; Zhong, Hongyu; Pabst, Tyler P.; Shevlin, Michael; Chirik, Paul J. (April 2022, ACS Catalysis)

   The cobalt-catalyzed asymmetric hydrogenation of dehydro-sitagliptin was studied and applied to the synthesis of sitagliptin (Januvia®). Catalyst discovery efforts were accelerated by the application of a general method for the synthesis of cationic bis(phosphine) cobalt η6-arene complexes. One-electron oxidation of bis(phosphine) cobalt(II) dialkyl complexes in the presence of arenes furnished the corre-sponding, bench stable cobalt precatalysts, [(P-P)Co(η6-C6H6)][BArF4]. Asymmetric hydrogenation utilized 0.5 mol% of the optimal catalyst, [(R,R)-(iPrDuPhos)Co(η6-C6H6)][BArF4] in THF solution and produced sitagliptin in >99% yield with 97% ee. Cobalt catalysts were compatible with a range of solvents and maintained excellent activity and selectivity after standing in air in the solid state for two weeks. Deuterium labeling studies support an enamine-imine tautomerization process resulting in reduction of the metalated imine. Notably, state-of-the-art neutral bis(phosphine) cobalt precatalysts were ineffective, emphasizing the utility of a class of cationic cobalt precatalyst. 

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