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We fabricated and evaluated multiplexed ion-selective electrodes (ISEs) by modifying printed circuit board (PCB). The multiplexed sensor consisted of all-solid-state K+ and NO3- ISEs, together with a Ag/AgCl reference. The sensor was further embedded in a microfluidic microchannel for in-line continuous analysis, and was characterized for up to one week of operation. Both ISEs showed a near-Nernstian response (~52 mV/dec) and reasonable stabilities (baseline drift ~2.9 mV/day). The sensor provides a versatile and low-cost tool for monitoring concentrations of different ions in many biomedical, environmental and agricultural applications.
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