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1. The Brin Prize works of Tim Austin

   https://doi.org/10.3934/jmd.2023024  

   Thouvenot, Jean-Paul (January 2023, Journal of Modern Dynamics)
2. ABAQUS models for chiral TIM systems

   https://doi.org/10.4231/6AT6-RW35  

   Kim, Dong; Siegmund, Thomas; Siegmund, Thomas (January 2024, Purdue University Research Repository)

   Topologically Interlocked Material systems are a class of architectured materials. TIM systems are assembled from individual building blocks and are confined by an external frame. In particular, 2D, plate-type assemblies are considered. This publication contains files for the numerical analysis of the mechanical behavior of TIM systems through the use of finite element analysis. ABAQUS model files (inp format) for the study of the chiral/achiral response are provided. Files chirality_s1_in.inp are for type I square assemblies. n=3,5,7,9 Files chirality_s2_in.inp are for type II square assemblies. n=4,6,8,10 Files chirality_h1_in.inp are for type I hexagon assemblies. n=2,3,4,5 Files chirality_h2_in.inp are for type II hexagon assemblies. n=2,3,4,5 File chirality_s1i5_center_dissection.inp is for an assembly with a dissection of the central tile of type I square assembly with n=5. File chirality_s2i6_center_dissection.inp is for an assembly with a dissection of the central tile of type II square assembly with n=6. File chirality_s1i5_center_surrounding_dissection.inp is for an assembly with dissections of the tiles surrounding the center tile of type I square assembly with n=5. File chirality_h1i3_center_dissection.inp is for an assembly with a dissection of the central tile of type I hexagon assembly with n=3. File chirality_h2i3_center_dissection.inp is for an assembly with a dissection of the central tile of type II hexagon assembly with n=3. File chirality_h1i3_center_surrounding_dissection.inp is for an assembly with dissections of the tiles surrounding the center tile of type I hexagon assembly with n=3. 

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3. CONVERSATIONSConversation with a prominent propagator: Tim Bell

   https://doi.org/10.1145/3457774  

   Bunde, David P.; Butler, Zack; Hovey, Christopher L.; Taylor, Cynthia (September 2021, ACM Inroads)
4. Multilevel Topological Interference Management: A TIM-TIN Perspective

   https://doi.org/10.1109/TCOMM.2021.3102623  

   Geng, Chunhua; Sun, Hua; Jafar, Syed A. (August 2021, IEEE Transactions on Communications)

   null (Ed.)

   The robust principles of treating interference as noise (TIN) when it is sufficiently weak, and avoiding it when it is not, form the background of this work. Combining TIN with the topological interference management (TIM) framework that identifies optimal interference avoidance schemes, we formulate a TIM-TIN problem for multilevel topological interference management, wherein only a coarse knowledge of channel strengths and no knowledge of channel phases is available to transmitters. To address the TIM-TIN problem, we first propose an analytical baseline approach, which decomposes a network into TIN and TIM components, allocates the signal power levels to each user in the TIN component, allocates signal vector space dimensions to each user in the TIM component, and guarantees that the product of the two is an achievable number of signal dimensions available to each user in the original network. Next, a distributed numerical algorithm called ZEST is developed. The convergence of the algorithm is demonstrated, leading to the duality of the TIM-TIN problem in terms of generalized degrees-of-freedom (GDoF). Numerical results are also provided to demonstrate the superior sum-rate performance and fast convergence of ZEST. 

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5. Biomechanical characterization of TIM protein–mediated Ebola virus–host cell adhesion

   https://doi.org/10.1038/s41598-018-36449-2  

   Dragovich, Matthew A.; Fortoul, Nicole; Jagota, Anand; Zhang, Wei; Schutt, Krista; Xu, Yan; Sanabria, Michelle; Moyer, Jr., Dennis M.; Moller-Tank, Sven; Maury, Wendy; et al (January 2019, Scientific Reports)

   Abstract Since the most recent outbreak, the Ebola virus (EBOV) epidemic remains one of the world’s public health and safety concerns. EBOV is a negative-sense RNA virus that can infect humans and non-human primates, and causes hemorrhagic fever. It has been proposed that the T-cell immunoglobulin and mucin domain (TIM) family proteins act as cell surface receptors for EBOV, and that the interaction between TIM and phosphatidylserine (PS) on the surface of EBOV mediates the EBOV–host cell attachment. Despite these initial findings, the biophysical properties of the TIM-EBOV interaction, such as the mechanical strength of the TIM-PS bond that allows the virus-cell interaction to resist external mechanical perturbations, have not yet been characterized. This study utilizes single-molecule force spectroscopy to quantify the specific interaction forces between TIM-1 or TIM-4 and the following binding partners: PS, EBOV virus-like particle, and EBOV glycoprotein/vesicular stomatitis virus pseudovirion. Depending on the loading rates, the unbinding forces between TIM and ligands ranged from 40 to 100 pN, suggesting that TIM-EBOV interactions are mechanically comparable to previously reported adhesion molecule–ligand interactions. The TIM-4–PS interaction is more resistant to mechanical force than the TIM-1–PS interaction. We have developed a simple model for virus–host cell interaction that is driven by its adhesion to cell surface receptors and resisted by membrane bending (or tension). Our model identifies critical dimensionless parameters representing the ratio of deformation and adhesion energies, showing how single-molecule adhesion measurements relate quantitatively to the mechanics of virus adhesion to the cell. 

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