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Title: Molecular dynamics simulation of an entire cell
The ultimate microscope, directed at a cell, would reveal the dynamics of all the cell’s components with atomic resolution. In contrast to their real-world counterparts, computational microscopes are currently on the brink of meeting this challenge. In this perspective, we show how an integrative approach can be employed to model an entire cell, the minimal cell, JCVI-syn3A, at full complexity. This step opens the way to interrogate the cell’s spatio-temporal evolution with molecular dynamics simulations, an approach that can be extended to other cell types in the near future.  more » « less
Award ID(s):
2221237
NSF-PAR ID:
10421248
Author(s) / Creator(s):
; ; ; ; ; ; ; ;
Date Published:
Journal Name:
Frontiers in Chemistry
Volume:
11
ISSN:
2296-2646
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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