Artificial Intelligence (AI) systems for mental healthcare (MHCare) have been ever-growing after realizing the importance of early interventions for patients with chronic mental health (MH) conditions. Social media (SocMedia) emerged as the go-to platform for supporting patients seeking MHCare. The creation of peer-support groups without social stigma has resulted in patients transitioning from clinical settings to SocMedia supported interactions for quick help. Researchers started exploring SocMedia content in search of cues that showcase correlation or causation between different MH conditions to design better interventional strategies. User-level Classification-based AI systems were designed to leverage diverse SocMedia data from various MH conditions, to predict MH conditions. Subsequently, researchers created classification schemes to measure the severity of each MH condition. Such ad-hoc schemes, engineered features, and models not only require a large amount of data but fail to allow clinically acceptable and explainable reasoning over the outcomes. To improve Neural-AI for MHCare, infusion of clinical symbolic knowledge that clinicans use in decision making is required. An impactful use case of Neural-AI systems in MH is conversational systems. These systems require coordination between classification and generation to facilitate humanistic conversation in conversational agents (CA). Current CAs with deep language models lack factual correctness, medical relevance, and safety in their generations, which intertwine with unexplainable statistical classification techniques. This lecture-style tutorial will demonstrate our investigations into Neuro-symbolic methods of infusing clinical knowledge to improve the outcomes of Neural-AI systems to improve interventions for MHCare:(a) We will discuss the use of diverse clinical knowledge in creating specialized datasets to train Neural-AI systems effectively. (b) Patients with cardiovascular disease express MH symptoms differently based on gender differences. We will show that knowledge-infused Neural-AI systems can identify gender-specific MH symptoms in such patients. (c) We will describe strategies for infusing clinical process knowledge as heuristics and constraints to improve language models in generating relevant questions and responses. 
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                            Learning to Automate Follow-up Question Generation using Process Knowledge for Depression Triage on Reddit Posts
                        
                    
    
            Conversational Agents (CAs) powered with deep language models (DLMs) have shown tremendous promise in the domain of mental health. Prominently, the CAs have been used to provide informational or therapeutic services (e.g., cognitive behavioral therapy) to patients. However, the utility of CAs to assist in mental health triaging has not been explored in the existing work as it requires a controlled generation of follow-up questions (FQs), which are often initiated and guided by the mental health professionals (MHPs) in clinical settings. In the context of ‘depression’, our experiments show that DLMs coupled with process knowledge in a mental health questionnaire generate 12.54% and 9.37% better FQs based on similarity and longest common subsequence matches to questions in the PHQ-9 dataset respectively, when compared with DLMs without process knowledge support.Despite coupling with process knowledge, we find that DLMs are still prone to hallucination, i.e., generating redundant, irrelevant, and unsafe FQs. We demonstrate the challenge of using existing datasets to train a DLM for generating FQs that adhere to clinical process knowledge. To address this limitation, we prepared an extended PHQ-9 based dataset, PRIMATE, in collaboration with MHPs. PRIMATE contains annotations regarding whether a particular question in the PHQ-9 dataset has already been answered in the user’s initial description of the mental health condition. We used PRIMATE to train a DLM in a supervised setting to identify which of the PHQ-9 questions can be answered directly from the user’s post and which ones would require more information from the user. Using performance analysis based on MCC scores, we show that PRIMATE is appropriate for identifying questions in PHQ-9 that could guide generative DLMs towards controlled FQ generation (with minimal hallucination) suitable for aiding triaging. The dataset created as a part of this research can be obtained from https://github.com/primate-mh/Primate2022 
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                            - Award ID(s):
- 2133842
- PAR ID:
- 10429256
- Date Published:
- Journal Name:
- Proceedings of the Eighth Workshop on Computational Linguistics and Clinical Psychology
- Page Range / eLocation ID:
- 137 to 147
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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