Hydrogels with the ability to change shape in response to biochemical stimuli are important for biosensing, smart medicine, drug delivery, and soft robotics. Here, a family of multicomponent DNA polymerization motor gels with different polymer backbones is created, including acrylamide‐
Endovascular embolization of cerebral aneurysms is a common approach for reducing the risk of often‐fatal hemorrhage. However, currently available materials used to occlude these aneurysms provide incomplete filling (coils) or require a complicated, time‐consuming delivery procedure (solvent‐exchange precipitating polymers). The objective of this work was to develop an easily deliverable in situ forming hydrogel that can occlude the entire volume of an aneurysm. The hydrogel is formed by mixing a solution of a temperature‐responsive polymer containing pendent thiol groups (poly(NIPAAm‐
- NSF-PAR ID:
- 10446080
- Publisher / Repository:
- Wiley Blackwell (John Wiley & Sons)
- Date Published:
- Journal Name:
- Journal of Biomedical Materials Research Part B: Applied Biomaterials
- Volume:
- 110
- Issue:
- 8
- ISSN:
- 1552-4973
- Page Range / eLocation ID:
- p. 1911-1921
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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