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Title: Impact of endoscopic craniofacial resection on simulated nasal airflow and heat transport
Background

Endoscopic craniofacial resections (CFR) are performed for extensive anterior skull base lesions. This surgery involves removal of multiple intranasal structures, potentially leading to empty nose syndrome (ENS). However, many patients remain asymptomatic postoperatively. Our objective was to analyze the impact of CFR on nasal physiology and airflow using computational fluid dynamics (CFD). This is the first CFD analysis of post‐CFR patients.

 Methods

Three‐dimensional sinonasal models were constructed from 3 postoperative images using MimicsTM. Hybrid computational meshes were created. Steady inspiratory airflow and heat transport were simulated at patient‐specific flow rates using shear stress transportk‐omega turbulent flow modeling in FluentTM. Simulated average heat flux (HF) and surface area where HF exceeded 50 W/m2(SAHF50) were compared with laminar simulations in 9 radiographically normal adults.

 Results

Three adults underwent CFR without developing ENS. Average HF (W/m2) were 132.70, 134.84, and 142.60 in the CFR group, ranging from 156.24 to 234.95 in the nonoperative cohort. SAHF50 (m2) values were 0.0087, 0.0120, and 0.0110 in the CFR group, ranging from 0.0082 to 0.0114 in the radiographically normal cohort. SAHF50 was distributed throughout the CFR cavities, with increased HF at the roof and walls compared with the nonoperative cohort.

 Conclusion

Average HF was low in the CFR group compared with the nonoperative group. However, absence of ENS in most CFR patients may be due to large stimulated mucosal surface area, commensurate with the nonoperative cohort. Diffuse distribution of stimulated area may result from turbulent mixing after CFR. To better understand heat transport post‐CFR, a larger cohort is necessary.

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PAR ID:
10460139
Author(s) / Creator(s):
 ;  ;  ;  ;  ;  ;  
Publisher / Repository:
Wiley Blackwell (John Wiley & Sons)
Date Published:
Journal Name:
International Forum of Allergy & Rhinology
Volume:
9
Issue:
8
ISSN:
2042-6976
Page Range / eLocation ID:
p. 900-909
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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