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Abstract Deoxyribonucleic acid (DNA) has emerged as a promising building block for next-generation ultra-high density storage devices. Although DNA has high durability and extremely high density in nature, its potential as the basis of storage devices is currently hindered by limitations such as expensive and complex fabrication processes and time-consuming read–write operations. In this article, we propose the use of a DNA crossbar array architecture for an electrically readable read-only memory (DNA-ROM). While information can be ‘written’ error-free to a DNA-ROM array using appropriate sequence encodings its read accuracy can be affected by several factors such as array size, interconnect resistance, and Fermi energy deviations from HOMO levels of DNA strands employed in the crossbar. We study the impact of array size and interconnect resistance on the bit error rate of a DNA-ROM array through extensive Monte Carlo simulations. We have also analyzed the performance of our proposed DNA crossbar array for an image storage application, as a function of array size and interconnect resistance. While we expect that future advances in bioengineering and materials science will address some of the fabrication challenges associated with DNA crossbar arrays, we believe that the comprehensive body of results we present in this paper establishes the technical viability of DNA crossbar arrays as low power, high-density storage devices. Finally, our analysis of array performance vis-à-vis interconnect resistance should provide valuable insights into aspects of the fabrication process such as proper choice of interconnects necessary for ensuring high read accuracies.
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Modeling and Simulation of DNA Origami based Electronic Read-only Memory
Deoxyribonucleic acid (DNA) has emerged as a promising building block for designing next-generation ultra-high density storage devices. Although DNA is highly durable and extremely high density in nature, its potential as the basis of storage devices is currently hindered by limitations such as expensive and complex fabrication processes and time-consuming read-write operations. In this article, we propose the use of a DNA crossbar array architecture for an electrically-readable Read-Only Memory (DNA-ROM). For DNA-ROM, we have chosen two DNA strands for representing Bit 1 and Bit 0 respectively. DNA charge transport has been studied through a contact-DNA-contact setup. The results obtained from the DNA charge transport study have been used to analyze the crossbar array. The performance has been analyzed by loading an image onto a 128×128 crossbar. For this application, we have observed a bit error rate of 4.52% and power consumption of 6.75 µW.
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- Award ID(s):
- 1807391
- PAR ID:
- 10467313
- Publisher / Repository:
- IEEE
- Date Published:
- ISBN:
- 978-1-6654-5225-0
- Page Range / eLocation ID:
- 385 to 388
- Format(s):
- Medium: X
- Location:
- Palma de Mallorca, Spain
- Sponsoring Org:
- National Science Foundation
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- Free Publicly Accessible Full Text
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Accepted Manuscript1.0
- Conference Paper:
- https://doi.org/10.1109/NANO54668.2022.9928676
