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Title: Ink Formulation and Selection for Biological Applications of Two-Photon Polymerization
Two-photon polymerization (TPP) uses nonlinear light interactions in photo-cross-linkable precursors to create high-resolution (∼100 nm) structures and high dimensional fidelity. Using a near-infrared light source in TPP results in less scattering and a higher penetration depth, making it attractive for creating biological models and tissue scaffolds. Due to unmatched flexibility and spatial resolution, they range from microvascular constructs to microneedles and stents. This review reviews the working principles and current inks used for TPP-printed constructs. We discuss the advantages of TPP over conventional additive manufacturing methods for tissue engineering, vascularized models, and other biomedical applications. This review provides a short recipe for selecting inks and photoinitiators for a desired structure.  more » « less
Award ID(s):
2234496
PAR ID:
10500294
Author(s) / Creator(s):
; ; ; ;
Publisher / Repository:
ACS Publications
Date Published:
Journal Name:
ACS Applied Optical Materials
Volume:
1
Issue:
9
ISSN:
2771-9855
Page Range / eLocation ID:
1501 to 1512
Subject(s) / Keyword(s):
Microfabrication two-photon polymerization resolution biophotonics vascularized modeling tissue engineering
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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