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This content will become publicly available on November 22, 2024

Title: Melamine-cored glucosides for membrane protein solubilization and stabilization: importance of water-mediated intermolecular hydrogen bonding in detergent performance

A melamine-based glucoside, MG-C11, has the ability to form a dynamic hydrogen-bonding network between detergent molecules, responsible for the markedly enhanced efficacy for GPCR stabilization compared to LMNG and previously developed TTG-C11.

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Publisher / Repository:
Royal Society of Chemistry
Date Published:
Journal Name:
Chemical Science
Page Range / eLocation ID:
13014 to 13024
Medium: X
Sponsoring Org:
National Science Foundation
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