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Title: Photonic Crystal Enhanced Fluorescence with DNA-based Nano-gripper for Ultrasensitive SARS-CoV-2 Biosensing
DNA-origami based nano-grippers, integrated with aptamer-based nanoswitches, generate fluorescent signals when detecting SARS-CoV-2. The integration of Photonic Crystal Enhanced Fluorescence Microscope enables a 104-fold enhancement compared to a single fluorophore reporter on glass substrate, providing a promising tool for ultrasensitive detection and rapid diagnostics.  more » « less
Award ID(s):
1900277
PAR ID:
10532048
Author(s) / Creator(s):
; ; ; ; ; ; ; ; ;
Publisher / Repository:
IEEE Photonics Conference
Date Published:
Format(s):
Medium: X
Location:
Orlando, FL
Sponsoring Org:
National Science Foundation
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