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Title: BLADE-ON-PETIOLE interacts with CYCLOIDEA to fine-tune CYCLOIDEA -mediated flower symmetry in monkeyflowers ( Mimulus )
Morphological novelties, or key innovations, are instrumental to the diversification of the organisms. In plants, one such innovation is the evolution of zygomorphic flowers, which is thought to promote outcrossing and increase flower morphological diversity. We isolated three allelic mutants from twoMimulusspecies displaying altered floral symmetry and identified the causal gene as the ortholog ofArabidopsis BLADE-ON-PETIOLE. We found that MlBOP and MlCYC2A physically interact and this BOP-CYC interaction module is highly conserved across the angiosperms. Furthermore, MlBOP self-ubiquitinates and suppressesMlCYC2Aself-activation. MlCYC2A, in turn, impedes MlBOP ubiquitination. Thus, this molecular tug-of-war between MlBOP and MlCYC2A fine-tunes the expression ofMlCYC2A, contributing to the formation of bilateral symmetry in flowers, a key trait in angiosperm evolution.  more » « less
Award ID(s):
1827645 1755373
PAR ID:
10538522
Author(s) / Creator(s):
; ; ; ; ; ; ; ; ; ; ; ; ; ;
Publisher / Repository:
AAAS
Date Published:
Journal Name:
Science Advances
Volume:
10
Issue:
33
ISSN:
2375-2548
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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