More Like this

1. The Best of Both Worlds: Discovery-Driven Learning through a Lab-Seminar Approach

   https://doi.org/10.1128/jmbe.00031-22  

   Egan, Marisa S. ; Hogan, Karen ; Maupin-Furlow, Julie ; Pohlschroder, Mechthild ( October 2022 , Journal of Microbiology & Biology Education)

   Yeong, Foong May (Ed.)

   ABSTRACT Microbiology courses are often designed as either a lecture class with a laboratory component or a seminar-style class. Each type of course provides students with unique learning opportunities. Lab courses allow students to perform simple experiments that relate to fundamental concepts taught in the corresponding lectures, while seminar courses challenge students to read and discuss primary literature. Microbiology courses offering a combination of seminar-style discussions and laboratory procedures are rare. Our goal in the “Microbial Diversity and Pathogenesis” undergraduate course is to integrate experiences of a seminar class with those of a discovery-driven lab course, thereby strengthening students’ learning experiences through diversified didactic approaches. In the first half of the course, students read and discuss published peer-reviewed articles that cover major topics in both basic and applied microbiology, including antibiotic resistance, pathogenesis, and biotechnology applications. Complementing this primary literature, students perform microbiology experiments related to the topics covered in the readings. The assigned readings, discussions, and experiments provide a foundation in the second half of the course for inquiry-based exploratory research using student-designed transposon screens and selections. The course culminates in each student drafting a hypothesis-driven research proposal based on their literature review, their learned experimental techniques, and the preliminary data generated as a class. Through such first-hand experimental experience, students gain fundamental lab skills that are applicable beyond the realm of microbiology, such as sterile technique and learning how to support conclusions with scientific evidence. We observed a tremendous synergy between the seminar and lab aspects of our course. This unique didactic experience allows students to understand and connect primary literature to their experiments, while the discovery-driven aspect of this approach fosters active engagement of students with scientific research. 

   more » « less
2. Increasing Student Confidence in Writing: Integrating Authentic Manuscript Writing into an Online 8-Week Research Program

   https://doi.org/10.1128/jmbe.00199-22  

   Kim, Choah ; Preston, Kiam ; Braga, Alice ; Fankhauser, Sarah C. ( April 2023 , Journal of Microbiology & Biology Education)

   McCartney, Melissa (Ed.)

   ABSTRACT In various formats, students at the secondary and postsecondary levels participate in multiweek authentic science research projects. There have been many papers explaining the operations of such programs, but few have provided explicit instruction on how to incorporate authentic communication practices into the student research process. In this paper, we describe how we integrated primary literature into an 8-week online research program for 8th to 11th graders. Each week, students were introduced to a specific section of a primary research article reflecting different stages of their research project, and they were guided on how to write that specific section for their own research paper. By the end of the program, students had an outline or first draft of a primary research paper based on their research. Following completion of the program, student participants reported greater self-efficacy and confidence in scientific writing. Here, we describe our approach and provide an adaptable framework for integrating primary literature into research projects. 

   more » « less
3. Design and implementation of an asynchronous online course-based undergraduate research experience (CURE) in computational genomics

   https://doi.org/10.1371/journal.pcbi.1012384  

   Plaisier, Seema B ; Alarid, Danielle O ; Denning, Joelle A ; Brownell, Sara E ; Buetow, Kenneth H ; Cooper, Katelyn M ; Wilson, Melissa A ( September 2024 , PLOS Computational Biology)

   Palagi, Patricia M (Ed.)

   As genomics technologies advance, there is a growing demand for computational biologists trained for genomics analysis but instructors face significant hurdles in providing formal training in computer programming, statistics, and genomics to biology students. Fully online learners represent a significant and growing community that can contribute to meet this need, but they are frequently excluded from valuable research opportunities which mostly do not offer the flexibility they need. To address these opportunity gaps, we developed an asynchronous course-based undergraduate research experience (CURE) for computational genomics specifically for fully online biology students. We generated custom learning materials and leveraged remotely accessible computational tools to address 2 novel research questions over 2 iterations of the genomics CURE, one testing bioinformatics approaches and one mining cancer genomics data. Here, we present how the instructional team distributed analysis needed to address these questions between students over a 7.5-week CURE and provided concurrent training in biology and statistics, computer programming, and professional development. Scores from identical learning assessments administered before and after completion of each CURE showed significant learning gains across biology and coding course objectives. Open-response progress reports were submitted weekly and identified self-reported adaptive coping strategies for challenges encountered throughout the course. Progress reports identified problems that could be resolved through collaboration with instructors and peers via messaging platforms and virtual meetings. We implemented asynchronous communication using the Slack messaging platform and an asynchronous journal club where students discussed relevant publications using the Perusall social annotation platform. The online genomics CURE resulted in unanticipated positive outcomes, including students voluntarily discussing plans to continue research after the course. These outcomes underscore the effectiveness of this genomics CURE for scientific training, recruitment and student-mentor relationships, and student successes. Asynchronous genomics CUREs can contribute to a more skilled, diverse, and inclusive workforce for the advancement of biomedical science. 

   more » « less
4. A Guided-Inquiry Activity for Introducing Students to Figures from Primary Scientific Literature

   https://doi.org/10.1021/acs.jchemed.2c00605  

   Maxwell, Danielle N. ; Spencer, Jeffrey L. ; Teich, Ethan A. ; Cooke, Madeline ; Fromwiller, Braeden ; Peterson, Nathan ; Nicholas-Figueroa, Linda ; Shultz, Ginger V. ; Pratt, Kerri A. ( May 2023 , Journal of Chemical Education)

   Holme, Thomas (Ed.)

   Reading and understanding scientific literature is an essential skill for any scientist to learn. While students’ scientific literacy can be improved by reading research articles, an article’s technical language and structure can hinder students’ understanding of the scientific material. Furthermore, many students struggle with interpreting graphs and other models of data commonly found in scientific literature. To introduce students to scientific literature and promote improved understanding of data and graphs, we developed a guided-inquiry activity adapted from a research article on snow chemistry and implemented it in a general chemistry laboratory course. Here, we describe how we adapted figures from the primary literature source and developed questions to scaffold the guided-inquiry activity. Results from semi-structured qualitative interviews suggest that students learn about snow chemistry processes and engage in scientific practices, including data analysis and interpretation, through this activity. This activity is applicable in other introductory science courses as educators can adapt most scientific articles into a guided-inquiry activity. 

   more » « less
5. Web-based authentic inquiry experiences in large introductory classes consistently associated with significant learning gains for all students

   https://doi.org/10.1186/s40594-021-00290-3  

   Wu, X. Ben ; Sandoval, Carolyn ; Knight, Stephanie ; Jaime, Xavier ; Macik, Maria ; Schielack, Jane F. ( April 2021 , International Journal of STEM Education)

   Continuous calls for reform in science education emphasize the need to provide science experiences in lower-division courses to improve the retention of STEM majors and to develop science literacy and STEM skills for all students. Open or authentic inquiry and undergraduate research are effective science experiences leading to multiple gains in student learning and development. Most inquiry-based learning activities, however, are implemented in laboratory classes and the majority of them are guided inquiries. Although course-based undergraduate research experiences have significantly expanded the reach of the traditional apprentice approach, it is still challenging to provide research experiences to nonmajors and in large introductory courses. We examined student learning through a web-based authentic inquiry project implemented in a high-enrollment introductory ecology course for over a decade.

   Results from 10 years of student self-assessment of learning showed that the authentic inquiry experiences were consistently associated with significant gains in self-perception of interest and understanding and skills of the scientific process for all students—both majors and nonmajors, both lower- and upper-division students, both women and men, and both URM and non-URM students. Student performance in evaluating the quality of an inquiry report, before and after the inquiry project, also showed significant learning gains for all students. The authentic inquiry experiences proved highly effective for lower-division students, nonmajors, and women and URM students, whose learning gains were similar to or greater than those of their counterparts. The authentic inquiry experiences were particularly helpful to students who were less prepared with regard to the ability to evaluate a scientific report and narrowed the performance gap.

   These findings suggest that authentic inquiry experiences can serve as an effective approach for engaging students in high-enrollment, introductory science courses. They can facilitate development of science literacy and STEM skills of all students, skills that are critical to students’ personal and professional success and to informed engagement in civic life.

    

   more » « less