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Using a Lewis acid-quenched CF2Ph- reagent, we show C–C bond formation through nucleophilic addition reactions to prepare molecules containing internal –CF2– linkages. We demonstrate C(sp2)–C(sp3) coupling using both SNAr reactions and Pd-catalysis. Finally, C(sp3)–C(sp3) bonds are forged using operationally simple SN2 reactions that tolerate medicinally-relevant motifs.
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EC-MS dataset of electrocatalytic transformations of butane on Pt
This distribution provides the code and reference data for the manuscript of "Understanding the interplay between electrocatalytic C(sp3)‒C(sp3) fragmentation and oxygenation reactions"
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- Award ID(s):
- 2338627
- PAR ID:
- 10573487
- Publisher / Repository:
- Zenodo
- Date Published:
- Format(s):
- Medium: X
- Right(s):
- Creative Commons Attribution 4.0 International
- Sponsoring Org:
- National Science Foundation
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