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1. Resting-state functional network segregation of the default mode network predicts valence bias across the lifespan

   https://doi.org/10.1162/imag_a_00403  

   Pierce, Jordan E; Wig, Gagan S; Harp, Nicholas R; Neta, Maital (January 2024, Imaging Neuroscience)

   Abstract The brain is organized into intrinsically connected functional networks that can be reliably identified during resting-state functional magnetic resonance imaging (fMRI). Healthy aging is marked by decreased network segregation, which is linked to worse cognitive functioning, but aging-related changes in emotion are less well characterized. Valence bias, which represents the tendency to interpret emotionally ambiguous information as positive or negative, is more positive in older than younger adults and is associated with differences in task-based fMRI activation in the amygdala, prefrontal cortex, and a cingulo-opercular (CO) network. Here, we examined valence bias, age, and resting-state network segregation of 12 brain networks in a sample of 221 healthy individuals from 6 to 80 years old. Resting-state network segregation decreased linearly with increasing age, extending prior reports of de-differentiation across the lifespan. Critically, a more positive valence bias was related to lower segregation of the default mode network (DMN), due to stronger functional connectivity of the DMN with CO and, to a lesser extent, the ventral attention network (VAN) in all participants. In contrast to this overall segregation effect, in participants over 39 years old (who tend to show a positive valence bias), bias was also related to weaker connectivity between the DMN and Reward networks. The present findings indicate that specific interactions between the DMN, a task control network (CO), an emotion processing network (Reward), and, to a weaker extent, an attention network (VAN), support a more positive valence bias, perhaps through regulatory control of self-referential processing and reduced emotional reactivity in aging. The current work offers further insight into the functional brain network alterations that may contribute to affective well-being and dysfunction across the lifespan. 

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2. Spring Break or Heart Break? Extending Valence Bias to Emotional Words

   https://doi.org/10.1177/1948550620972296  

   Harp, Nicholas R.; Brown, Catherine C.; Neta, Maital (November 2020, Social Psychological and Personality Science)

   null (Ed.)

   Ambiguous stimuli are useful for assessing emotional bias. For example, surprised faces could convey a positive or negative meaning, and the degree to which an individual interprets these expressions as positive or negative represents their “valence bias.” Currently, the most well-validated ambiguous stimuli for assessing valence bias include nonverbal signals (faces and scenes), overlooking an inherent ambiguity in verbal signals. This study identified 32 words with dual-valence ambiguity (i.e., relatively high intersubject variability in valence ratings and relatively slow response times) and length-matched clearly valenced words (16 positive, 16 negative). Preregistered analyses demonstrated that the words-based valence bias correlated with the bias for faces, r s (213) = .27, p < .001, and scenes, r s (204) = .46, p < .001. That is, the same people who interpret ambiguous faces/scenes as positive also interpret ambiguous words as positive. These findings provide a novel tool for measuring valence bias and greater generalizability, resulting in a more robust measure of this bias. 

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3. Age-related differences in the temporal dynamics of spectral power during memory encoding

   https://doi.org/10.1371/journal.pone.0227274  

   Healey, M Karl; Kahana, Michael J (January 2020, PloS one)

   We examined oscillatory power in electroencephalographic recordings obtained while younger (18-30 years) and older (60+ years) adults studied lists of words for later recall. Power changed in a highly consistent way from word-to-word across the study period. Above 14 Hz, there were virtually no age differences in these neural gradients. But gradients below 14 Hz reliably discriminated between age groups. Older adults with the best memory performance showed the largest departures from the younger adult pattern of neural activity. These results suggest that age differences in the dynamics of neural activity across an encoding period reflect changes in cognitive processing that may compensate for age-related decline. 

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4. Age-Related Differences in Framing Selective Memory in Terms of Gains and Losses

   https://doi.org/10.1080/0361073X.2023.2233366  

   Murphy, Dillon H.; Castel, Alan D.; Knowlton, Barbara J. (July 2023, Experimental Aging Research)

   We examined whether framing younger and older adults learning goals in terms of maximizing gains or minimizing losses impacts their ability to selectively remember high-value information. Specifically, we presented younger and older adults with lists of words paired with point values and participants were either told that they would receive the value associated with each word if they recalled it on a test or that they would lose the points associated with each word if they failed to recall it on the test. We also asked participants to predict the likelihood of recalling each word to deter- mine if younger and older adults were metacognitively aware of any potential framing effects. Results revealed that older adults expected to be more selective when their goals were framed in terms of losses, but younger adults expected to be more selective when their goals were framed in terms of gains. However, this was not the case as both younger and older adults were more selective for high-value informa- tion when their goals were framed in terms of maximizing gains compared with minimizing losses. Thus, the framing of learning goals can impact metacognitive decisions and subsequent memory in both younger and older adults. 

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5. Reactive, Agentic, Apathetic, or Challenged? Aging, Emotion, and Coping During the COVID-19 Pandemic

   https://doi.org/10.1093/geront/gnaa196  

   Young, Nathaniel A; Waugh, Christian E; Minton, Alyssa R; Charles, Susan T; Haase, Claudia M; Mikels, Joseph A (December 2020, The Gerontologist)

   Meeks, Suzanne (Ed.)

   Abstract Background and Objectives Advanced age is generally associated with improved emotional well-being, but the coronavirus 2019 pandemic unleashed a global stressor that gravely threatened the physical well-being and ostensibly challenged the emotional well-being of older adults disproportionately. The current study investigated differences in emotional experiences and coping strategies between younger and older adults during the pandemic, and whether these differences were accounted for by age differences in appraisal of the pandemic. Research Design and Methods We asked younger (n = 181) and older (n = 176) adult participants to report their stress, appraisals of the pandemic, emotions, and the ways in which they were coping with the pandemic. Results Results indicated that older adults experienced less stress and less negative affect and used greater problem-focused coping and less avoidant coping in response to the pandemic than younger adults. Furthermore, age differences in affect and coping were partially accounted for by age differences in appraisals of the pandemic. Discussion and Implications Despite their objectively higher risk of illness and death due to the pandemic, older adults experienced less negative affect and used more agentic coping strategies than younger adults. 

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