An approach to the coalescent, the fractional coalescent (f-coalescent), is introduced. The derivation is based on the discrete-time Cannings population model in which the variance of the number of offspring depends on the parameter α. This additional parameter α affects the variability of the patterns of the waiting times; values of lead to an increase of short time intervals, but occasionally allow for very long time intervals. When , the f-coalescent and the Kingman’s n-coalescent are equivalent. The distribution of the time to the most recent common ancestor and the probability that n genes descend from m ancestral genes in a time interval of length T for the f-coalescent are derived. The f-coalescent has been implemented in the population genetic model inference software Migrate. Simulation studies suggest that it is possible to accurately estimate α values from data that were generated with known α values and that the f-coalescent can detect potential environmental heterogeneity within a population. Bayes factor comparisons of simulated data with and real data (H1N1 influenza and malaria parasites) showed an improved model fit of the f-coalescent over the n-coalescent. The development of the f-coalescent and its inclusion into the inference program Migratefacilitates testing for deviations from the n-coalescent.
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This content will become publicly available on August 1, 2026
A Fractional Spur Cancellation Technique for Fractional-N Frequency Synthesizers Enabled by Dual Loop Phase Clamping
- Award ID(s):
- 2315370
- PAR ID:
- 10626787
- Publisher / Repository:
- IEEE
- Date Published:
- Journal Name:
- IEEE Transactions on Circuits and Systems I: Regular Papers
- Volume:
- 72
- Issue:
- 8
- ISSN:
- 1549-8328
- Page Range / eLocation ID:
- 3791 to 3801
- Format(s):
- Medium: X
- Sponsoring Org:
- National Science Foundation
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