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This content will become publicly available on June 1, 2026

Title: Amplification of enzymatic and microbial fuel cells using organic electrochemical transistors
Organic electrochemical transistors (OECTs) are thin-film devices operated in aqueous and biological environments for sensing chemicals and biomolecules. However, most sensor configurations involve introducing the target biomolecule directly in the OECT device. This has drawbacks because it may not be possible to have an electrolyte compatible with the target biomolecule or an environment optimal for the OECT. Here, we demonstrate a general and modular approach to building electrochemical sensors by coupling OECTs electronically with either an enzymatic fuel cell (EFC) or microbial fuel cell (MFC). We demonstrate that this modular approach can amplify currents by three orders of magnitude and enhance the signal-to-noise ratio. We also show that the power generated by the fuel cell can help tune the sensor’s response for different applications. This work demonstrates a simple and versatile approach for amplifying currents from MFCs and EFCs useful for the development of bioelectronic sensors.  more » « less
Award ID(s):
2223678
PAR ID:
10652530
Author(s) / Creator(s):
; ; ; ; ; ; ;
Publisher / Repository:
Cell Press
Date Published:
Journal Name:
Device
Volume:
3
Issue:
6
ISSN:
2666-9986
Page Range / eLocation ID:
100714
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
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