Explore Research Products in the PAR
It may take a few hours for recently added research products to appear in PAR search results.


Title: The Fifth Annual Symposium of the Midwest Aging Consortium
Abstract As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of therapeutic interventions to support healthy aging. The Fifth Annual Midwest Aging Consortium Aging Research symposium, held from April 28 to 30, 2024, was hosted by The Ohio State University in Columbus, Ohio, and featured presentations from investigators across the Midwestern United States. This report summarizes the research presented at the symposium, whose topics included cellular senescence and the aging brain, metabolism and metabolic interventions, nutrition, redox mechanisms and biomarkers, and stress mechanisms. Abstract presentations and short talks highlighted early-stage and young investigators, whereas 2 keynote presentations anchored the symposium. Overall, this symposium showed the robustness of aging research in the Midwest and underscored the advantages of a collaborative approach to geroscience research.  more » « less
Award ID(s):
2046984
PAR ID:
10664619
Author(s) / Creator(s):
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; more » ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; « less
Editor(s):
Duque, Gustavo
Publisher / Repository:
Oxford Academic
Date Published:
Journal Name:
The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
Volume:
80
Issue:
2
ISSN:
1079-5006
Format(s):
Medium: X
Sponsoring Org:
National Science Foundation
More Like this
  1. ; ; ; ; ; ; ; ; ; ; et al (, The Journals of Gerontology: Series A)
    Duque, Gustavo (Ed.)
    Abstract The geroscience hypothesis suggests that addressing the fundamental mechanisms driving aging biology will prevent or mitigate the onset of multiple chronic diseases, for which the largest risk factor is advanced age. Research that investigates the root causes of aging is therefore of critical importance given the rising healthcare burden attributable to age-related diseases. The third annual Midwest Aging Consortium symposium was convened as a showcase of such research performed by investigators from institutions across the Midwestern United States. This report summarizes the work presented during a virtual conference across topics in aging biology, including immune function in the lung—particularly timely given the Corona Virus Immune Disease-2019 pandemic—along with the role of metabolism and nutrient-regulated pathways in cellular function with age, the influence of senescence on stem cell function and inflammation, and our evolving understanding of the mechanisms underlying observation of sex dimorphism in aging-related outcomes. The symposium focused on early-stage and emerging investigators, while including keynote presentations from leaders in the biology of aging field, highlighting the diversity and strength of aging research in the Midwest. 
    more » « less
  2. ; ; ; ; ; ; ; ; ; ; et al (, The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences)
    Duque, Gustavo (Ed.)
    Abstract The Midwest Aging Consortium (MAC) has emerged as a critical collaborative initiative aimed at advancing our understanding of aging and developing strategies to combat the rising prevalence of age-related diseases. Founded in 2019, MAC brings together researchers from various disciplines and institutions across the Midwestern United States to foster interdisciplinary geroscience research. This report summarizes the highlights of the Fourth Annual Symposium of MAC, which was held at Iowa State University in May 2023. The symposium featured presentations on a wide array of topics, including studies on slow-aging animals, cellular senescence and senotherapeutics, the role of the immune system in aging, metabolic changes in aging, neuronal health in aging, and biomarkers for measuring the aging process. Speakers shared findings from studies involving a variety of animals, ranging from commonly used species such as mice, rats, worms, yeast, and fruit flies, to less-common ones like naked mole-rats, painted turtles, and rotifers. MAC continues to emphasize the importance of supporting emerging researchers and fostering a collaborative environment, positioning itself as a leader in aging research. This symposium not only showcased the current state of aging biology research but also highlighted the consortium’s role in training the next generation of scientists dedicated to improving the healthspan and well-being of the aging population. 
    more » « less
  3. ; ; ; ; ; ; ; (, Advanced Materials)
    ABSTRACT Women's health remains inadequately served due to the historical predominance of males as the biological reference in medical research, leading to persistent sex‐based gaps in the understanding, diagnosis, and management of disease. As healthcare moves toward decentralization, e.g., through the collection of person‐generated health data, point‐of‐care diagnostics, and wearable devices, there is a critical need for tools tailored to women's unique conditions and presentations. Ultrasound technologies, recognized for their versatility and safety, have evolved from imaging to multifunctional platforms, with growing roles in diagnosis and therapy. Diagnostic ultrasound non‐invasively assesses anatomical features and functional information, and therapeutic ultrasound can perform targeted interventions, including neuromodulation, immunomodulation, thermal ablation, and drug delivery. By exploring the fundamental physical principles of ultrasound, including acoustic streaming, cavitation, and thermal interactions, and linking these mechanisms to cellular and tissue responses, this review highlights the capability of ultrasound to address female‐specific health disparities, especially in conditions that are undertreated or differentially expressed in women. Advancements in ultrasound technologies could significantly enhance clinical outcomes and improve the quality of life for women affected by conditions currently underserved by traditional medical interventions. 
    more » « less
  4. ; (, Integrative And Comparative Biology)
    Synopsis Mechanosensory information is a critical component of organismal movement control systems. Understanding the role mechanosensation plays in modulating organismal behavior requires inherently multidisciplinary research programs that reach across biological scales. Recently, there have been rapid advances in discerning how mechanosensory mechanisms are integrated into neural control systems and the impact mechanosensory information has on behavior. Thus, the Symposium “The Role of Mechanosensation in Robust Locomotion” at the 2023 Annual Meeting of the Society for Integrative and Comparative Biology was convened to discuss these recent advances, compare and contrast different systems, share experimental advice, and inspire collaborative approaches to expand and synthesize knowledge. The diverse set of speakers presented on a variety of vertebrate, invertebrate, and robotic systems. Discussion at the symposium resulted in a series of manuscripts presented in this issue that address issues facing the broader field, mechanisms of mechanosensation, organismal function and biomechanics, and sensing in ecological and social contexts. 
    more » « less
  5. ; ; ; ; ; ; (, Biophysical Reviews)
    The MGO symposium was held on February 18th with seven featured speakers from all over the globe. Drs. Bin Zhang and Alexey Onufriev chaired the session with Drs. Yamini Dalal and Anna Panchenko as the 2022 MGO co-chairs. The session and goals of the MGO subgroup were introduced by Dr. Panchenko, followed by talks from the invited speakers. The presentations showcased research at the forefront of the field and elicited high audience engagement. Here, we summarize the presentations of these invited speakers. 
    more » « less
  • Citation Formats
  • MLA
  • APA
  • Chicago
  • BibTeX
  • Text Encoded Conversion
  • XML
  • Save / Share this Record
  • Send to Email