%ASuchara, M.%AAlexeev, Y.%AChong, F.%AFinkel, H.%AHoffmann, H.%ALarson, J.%AOsborn, J.%ASmith, G.%D2018%I %K %MOSTI ID: 10092451 %PMedium: X %THybrid Quantum-Classical Computing Architectures %X—We describe how classical supercomputing can aid unreliable quantum processors of intermediate size to solve large problem instances reliably. We advocate using a hybrid quantum-classical architecture where larger quantum circuits are broken into smaller sub-circuits that are evaluated separately, either using a quantum processor or a quantum simulator running on a classical supercomputer. Circuit compilation techniques that determine which qubits are simulated classically will greatly impact the system performance as well as provide a tradeoff between circuit reliability and runtime. Country unknown/Code not availableOSTI-MSA