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  1. Radiation therapy is a powerful and effective treatment which targets malignant tumors. Thus, improvements in radiation therapy devices such as compensators can have an immediate impact on the treatment of cancer patients. This paper investigates the design and manufacturing of customized radiation modulation devices. This research proposes a thin-walled device design that can use recyclable fillable media such as water. This approach has several advantages including localized radiation exposure, eco-friendly design, and lower fabrication costs. The Fused Deposition Modeling (FDM) technique was used to develop a hollow bottle-like electron bolus with higher precision (μm resolution). The radiation modulation properties of acrylonitrile butadiene styrene (ABS) and polycarbonate (PC) materials were investigated. The compensator devices were subjected to high radiation doses and mechanical loads to check for dimensional deformations which can impact subsequent radiation profiles. Our findings showed that both ABS and PC materials had superior radiation tolerance as evaluated by the dimensional deviation analysis. Further, the devices had adequate mechanical properties as confirmed by deformation tests and finite element analysis. This paper provides a framework for the design and manufacture of custom compensators for radiation therapy. 
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