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Free, publicly-accessible full text available April 1, 2023
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Free, publicly-accessible full text available February 1, 2023
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Abstract Background Water resources development promotes agricultural expansion and food security. But are these benefits offset by increased infectious disease risk? Dam construction on the Senegal River in 1986 was followed by agricultural expansion and increased transmission of human schistosomes. Yet the mechanisms linking these two processes at the individual and household levels remain unclear. We investigated the association between household land use and schistosome infection in children. Methods We analyzed cross-sectional household survey data ( n = 655) collected in 16 rural villages in August 2016 across demographic, socio-economic and land use dimensions, which were matched to Schistosoma haematobium ( nmore »Free, publicly-accessible full text available December 1, 2022
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Secor, W. Evan (Ed.)Schistosome parasites infect more than 200 million people annually, mostly in sub-Saharan Africa, where people may be co-infected with more than one species of the parasite. Infection risk for any single species is determined, in part, by the distribution of its obligate intermediate host snail. As the World Health Organization reprioritizes snail control to reduce the global burden of schistosomiasis, there is renewed importance in knowing when and where to target those efforts, which could vary by schistosome species. This study estimates factors associated with schistosomiasis risk in 16 villages located in the Senegal River Basin, a region hyperendemic formore »Free, publicly-accessible full text available September 27, 2022
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Free, publicly-accessible full text available June 1, 2022
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Free, publicly-accessible full text available September 17, 2022
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null (Ed.)Dams enable the production of food and renewable energy, making them a crucial tool for both economic development and climate change adaptation in low- and middle-income countries. However, dams may also disrupt traditional livelihood systems and increase the transmission of vector- and water-borne pathogens. These livelihood and health impacts diminish the benefits of dams to rural populations dependent on rivers, as hydrological and ecological alterations change flood regimes, reduce nutrient transport and lead to the loss of biodiversity. We propose four agricultural innovations for promoting equity, health, sustainable development, and climate resilience in dammed watersheds: (1) restoring migratory aquatic species,more »
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We consider disordered solids in which the microscopic elements can deform plastically in response to stresses on them. We show that by driving the system periodically, this plasticity can be exploited to train in desired elastic properties, both in the global moduli and in local “allosteric” interactions. Periodic driving can couple an applied “source” strain to a “target” strain over a path in the energy landscape. This coupling allows control of the system’s response, even at large strains well into the nonlinear regime, where it can be difficult to achieve control simply by design.
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Abstract Infectious pathogens can disrupt the microbiome in addition to directly affecting the host. Impacts of disease may be dependent on the ability of the microbiome to recover from such disturbance, yet remarkably little is known about microbiome recovery after disease, particularly in nonhuman animals. We assessed the resilience of the amphibian skin microbial community after disturbance by the pathogen,
Batrachochytrium dendrobatidis (Bd). Skin microbial communities of laboratory-reared mountain yellow-legged frogs were tracked through three experimental phases: prior to Bd infection, after Bd infection (disturbance), and after clearing Bd infection (recovery period). Bd infection disturbed microbiome composition and altered the relative abundancesmore »