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Functional data contains two components: shape (or amplitude) and phase. This paper focuses on a branch of functional data analysis (FDA), namely Shape-Based FDA, that isolates and focuses on shapes of functions. Specifically, this paper focuses on Scalar-on-Shape (ScoSh) regression models that incorporate the shapes of predictor functions and discard their phases. This aspect sets ScoSh models apart from the traditional Scalar-on-Function (ScoF) regression models that incorporate full predictor functions. ScoSh is motivated by object data analysis, {\it, e.g.}, for neuro-anatomical objects, where object morphologies are relevant and their parameterizations are arbitrary. ScoSh also differs from methods that arbitrarily pre-register data and uses it in subsequent analysis. In contrast, ScoSh models perform registration during regression, using the (non-parametric) Fisher-Rao inner product and nonlinear index functions to capture complex predictor-response relationships. This formulation results in novel concepts of {\it regression phase} and {\it regression mean} of functions. Regression phases are time-warpings of predictor functions that optimize prediction errors, and regression means are optimal regression coefficients. We demonstrate practical applications of the ScoSh model using extensive simulated and real-data examples, including predicting COVID outcomes when daily rate curves are predictors.