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This study assesses the impact of fold-thrust belt driven deformation on the topographic evolution, bedrock exhumation and basin formation in the southeastern Peruvian Andes. We do this through a flexural and thermokinematically modelled balanced cross-section. In addition, published thermochronology samples from low-elevation (river canyons) and high-elevation (interfluves) and Cenozoic sedimentary basin datasets along the balanced cross-section were used to evaluate the age, location, and geometry of fault-driven uplift, as well as potential relationships to the timing of ∼2 km of canyon incision. The integrated structural, thermochronologic, and basin data were used to test the sensitivity of model results to various shortening rates and durations, a range of thermophysical parameters, and different magnitudes and timing of canyon incision. Results indicate that young apatite (U-Th)/He (AHe) canyon samples from ∼2 km in elevation or lower are consistent with river incision occurring between ∼8–2 Ma and are independent of the timing of ramp-driven uplift and accompanying erosion. In contrast, replicating the young AHe canyon samples located at >2.7 km elevation requires ongoing ramp-driven uplift. Replicating older interfluve cooling ages concurrent with young canyon ages necessitates slow shortening rates (0.25–0.6 mm/y) from ∼10 Ma to Present, potentially reflecting a decrease in upper plate compression during slab steepening. The best-fit model that reproduces basin ages and depositional contacts requires a background shortening rate of 3–4 mm/y with a marked decrease in rates to ≤0.5 mm/y at ∼10 Ma. Canyon incision occurred during this period of slow shortening, potentially enhanced by Pliocene climate change. 

Quantifying the impacts of past changes in tectonics or climate on mountain topography has proven challenging. The incision of the eastern Central Andean Plateau has been interpreted as both a result of deformation-related uplift and erosion and climate-driven erosion. Here, we contribute >100 new apatite and zircon (U-Th)/He and fission-track dates from 51 new and eight previous bedrock samples. These samples were combined with previous thermochronometer data from three ∼190-km-long and ∼200-km-apart across-strike transects along the eastern margin of the Andean Plateau in southern Peru. We discuss age-distance, age-elevation, and inverse thermal history model results along these transects to constrain the timing and extent of recent canyon incision compared to the region’s long-term (∼40 Myrs) exhumation history. Results indicate that, along the plateau flank, long-term, deformation-related exhumation is superimposed by a regional, synchronous canyon incision-related signal since ∼4–3 Ma. This incision is traceable from at least the Abancay Deflection in southern Peru to southern Bolivia along the eastern Central Andes. Based on the regional and synchronous character of canyon incision across areas with different deformation histories and exhumation magnitude, we suggest that paleoclimate change was a significant contributor to incision. However, structural processes resulting in surface uplift, erosion, and exhumation continued post-mid Miocene and contributed to the observed exhumation magnitude.