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ABSTRACT The orbits of some warm Jupiters are highly inclined (20°–50°) to those of their exterior companions. Comparable misalignments are inferred between the outer and inner portions of some transition discs. These large inclinations may originate from planet–planet and planet–disc secular resonances that sweep across interplanetary space as parent discs disperse. The maximum factor by which a seed mutual inclination can be amplified is of the order of the square root of the angular momentum ratio of the resonant pair. We identify those giant planet systems (e.g. Kepler-448 and Kepler-693) that may have crossed a secular resonance, and estimate the required planet masses and semimajor axes in transition discs needed to warp their innermost portions (e.g. in CQ Tau). Passage through an inclination secular resonance could also explain the hypothesized large mutual inclinations in apsidally-orthogonal warm Jupiter systems (e.g. HD 147018).