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The human body represents a collection of interacting systems that range in scale from nanometers to meters. Investigations from a systems perspective focus on how the parts work together to enact changes across spatial scales, and further our understanding of how systems function and fail. Here, we highlight systems approaches presented at the 2022 Summer Biomechanics, Bio-engineering, and Biotransport Conference in the areas of solid mechanics; fluid mechanics; tissue and cellular engineering; biotransport; and design, dynamics, and rehabilitation; and biomechanics education. Systems approaches are yielding new insights into human biology by leveraging state-of-the-art tools, which could ultimately lead to more informed design of therapies and medical devices for preventing and treating disease as well as rehabilitating patients using strategies that are uniquely optimized for each patient. Educational approaches can also be designed to foster a foundation of systems-level thinking. 

Abstract Rising global emission have led to a renewed popularity of timber in building design, including timber-concrete tall buildings up to 18 stories. In spite of this surge in wood construction, there remains a gap in understanding of long-term structural behavior, particularly wood creep. Unlike concrete, code prescriptions for wood design are lacking in robust estimates for structural shortening. Models for wood creep have become increasingly necessary due to the potential for unforeseen shortening, especially with respect to differential shortening. These effects can have serious impacts as timber building heights continue to grow. This study lays the groundwork for wood compliance prediction models for use in timber design. A thorough review of wood creep studies was conducted and viable experimental results were compiled into a database. Studies were chosen based on correlation of experimental conditions with a realistic building environment. An unbiased parameter identification method, originally applied to concrete prediction models, was used to fit multiple compliance functions to each data curve. Based on individual curve fittings, statistical analysis was performed to determine the best fit function and average parameter values for the collective database. A power law trend in wood creep, with lognormal parameter distribution, was confirmed by the results.