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The objective of this paper is to investigate the post-earthquake thermal-mechanical response of cold-formed steel (CFS) members. A 10-story cold-formed steel building (CFS-NHERI) will undergo seismic tests, followed by post-earthquake live fire tests. To support the fire test setup, computational models are developed to simulate the impact of varying post-earthquake damage levels on the fire response of the structure. As a panelized system, damage to different finish and nonstructural systems significantly affects the thermal behavior and load-bearing capacity of the CFS components. The computational models integrate the modeling capability in CUFSM and SAFIR for the elastic buckling, heat transfer, and transient structural analysis under fire. A parametric analysis considering different seismic damage levels is conducted to study the buckling and strength behavior of the CFS members under fire-induced nonuniform temperature fields. These pre-test models inform the duration and severity of the fire tests to maintain structural stability while achieving substantial thermal loading on the CFS load-bearing system. They also provide guidance for the sensor layout plan for the fire tests. This study advances methods for fire resilience of thin-walled CFS structures under multi-hazard scenarios.