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Free, publicly-accessible full text available December 31, 2026
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Sapoval, Nicolae; Liu, Yunxi; Lou, Esther G.; Hopkins, Loren; Ensor, Katherine B.; Schneider, Rebecca; Stadler, Lauren B.; Treangen, Todd J. (, Nature Communications)Abstract As clinical testing declines, wastewater monitoring can provide crucial surveillance on the emergence of SARS-CoV-2 variant of concerns (VoCs) in communities. In this paper we present QuaID, a novel bioinformatics tool for VoC detection based on quasi-unique mutations. The benefits of QuaID are three-fold: (i) provides up to 3-week earlier VoC detection, (ii) accurate VoC detection (>95% precision on simulated benchmarks), and (iii) leverages all mutational signatures (including insertions & deletions).more » « less
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Vankov, Emilian R.; Guindani, Michele; Ensor, Katherine B. (, Bayesian Analysis)
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Schweinberger, Michael; Babkin, Sergii; Ensor, Katherine B. (, Journal of Computational and Graphical Statistics)
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