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Reconsidering the Chemical Nature of Strand Breaks Derived from Abasic Sites in Cellular DNA: Evidence for 3′-Glutathionylation

https://doi.org/10.1021/jacs.2c02703

Jha, Jay S. ; Yin, Jiekai ; Haldar, Tuhin ; Yang, Zhiyu ; Wang, Yinsheng ; Gates, Kent S. ( June 2022 , Journal of the American Chemical Society)

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Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System

https://doi.org/10.1021/acs.chemrestox.1c00408

Jha, Jay S. ; Nel, Christopher ; Haldar, Tuhin ; Peters, Daniel ; Housh, Kurt ; Gates, Kent S. ( February 2022 , Chemical Research in Toxicology)

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Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Strand Cleavage at an Abasic Site in DNA

https://doi.org/10.1021/acs.chemrestox.1c00409

Haldar, Tuhin ; Jha, Jay S. ; Yang, Zhiyu ; Nel, Christopher ; Housh, Kurt ; Cassidy, Orla J. ; Gates, Kent S. ( February 2022 , Chemical Research in Toxicology)

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Synthesis of DNA Duplexes Containing Site-Specific Interstrand Cross-Links via Sequential Reductive Amination Reactions Involving Diamine Linkers and Abasic Sites on Complementary Oligodeoxynucleotides

https://doi.org/10.1021/acs.chemrestox.1c00293

Housh, Kurt ; Gates, Kent S. ( November 2021 , Chemical Research in Toxicology)

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Effects of Local Sequence, Reaction Conditions, and Various Additives on the Formation and Stability of Interstrand Cross-Links Derived from the Reaction of an Abasic Site with an Adenine Residue in Duplex DNA

https://doi.org/10.1021/acsomega.2c05736

Amin, Saosan Binth Md. ; Islam, Tanhaul ; Price, Nathan E. ; Wallace, Amanda ; Guo, Xu ; Gomina, Anuoluwapo ; Heidari, Marjan ; Johnson, Kevin M. ; Lewis, Calvin D. ; Yang, Zhiyu ; et al ( October 2022 , ACS Omega)
Formation and Repair of an Interstrand DNA Cross-Link Arising from a Common Endogenous Lesion

https://doi.org/10.1021/jacs.1c06926

Housh, Kurt ; Jha, Jay S. ; Yang, Zhiyu ; Haldar, Tuhin ; Johnson, Kevin M. ; Yin, Jiekai ; Wang, Yinsheng ; Gates, Kent S. ( September 2021 , Journal of the American Chemical Society)

Full Text Available