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  1. Abstract

    Green pea galaxies are starbursting, low-mass galaxies that are good analogues to star-forming galaxies in the early universe. We perform a survey of 23 green peas using the Multi Unit Spectroscopic Explorer (MUSE) Integral Field Unit spectrograph on the Very Large Telescope to search for companion galaxies. The survey reaches an average point-source depth of ∼10−18erg cm−2s−1for emission lines. The MUSE field of view allows us to probe a 1 × 1 arcmin2field around these galaxies and to search their surroundings for faint companions that could have interacted with them and induced their starburst episodes. We search for companions using a variety of methods including template matching to emission- and absorption-line spectra. When restricting the search to the same physical area (R= 78 kpc) for all galaxies, we find that the fraction of green pea galaxies with companions is0.110.05+0.07. We define a control sample of star-forming galaxies with the same stellar masses and redshifts as the green peas, but consistent with the star formation main sequence. We find that green pea galaxies are as likely to have companions as the control sample; for which the fraction of objects with companions is0.080.03+0.05. Given thatmore »we do not find statistical evidence for an elevated companion fraction in the green peas in this study, we argue that the “companions” are likely unrelated to the bursts in these galaxies.

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  2. Abstract Motivation

    Double minute (DM) chromosomes are acentric extrachromosomal DNA artifacts that are frequently observed in the cells of numerous cancers. They are highly amplified and contain oncogenes and drug-resistance genes, making their presence a challenge for effective cancer treatment. Algorithmic discovery of DM can potentially improve bench-derived therapies for cancer treatment. A hindrance to this task is that DMs evolve, yielding circular chromatin that shares segments from progenitor DMs. This creates DMs with overlapping amplicon coordinates. Existing DM discovery algorithms use whole genome shotgun sequencing (WGS) in isolation, which can potentially incorrectly classify DMs that share overlapping coordinates.


    In this study, we describe an algorithm called ‘HolistIC’ that can predict DMs in tumor genomes by integrating WGS and Hi–C sequencing data. The consolidation of these sources of information resolves ambiguity in DM amplicon prediction that exists in DM prediction with WGS data used in isolation. We implemented and tested our algorithm on the tandem Hi–C and WGS datasets of three cancer datasets and a simulated dataset. Results on the cancer datasets demonstrated HolistIC’s ability to predict DMs from Hi–C and WGS data in tandem. The results on the simulated data showed the HolistIC can accurately distinguish DMs that have overlappingmore »amplicon coordinates, an advance over methods that predict extrachromosomal amplification using WGS data in isolation.

    Availability and implementation

    Our software, named ‘HolistIC’, is available at

    Supplementary information

    Supplementary data are available at Bioinformatics online.

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    The cosmic ionizing emissivity from star-forming galaxies has long been anchored to UV luminosity functions. Here, we introduce an emissivity framework based on Lyα emitters (LAEs), which naturally hones in on the subset of galaxies responsible for the ionizing background due to the intimate connection between production and escape of Lyα and LyC photons. Using constraints on the escape fractions of bright LAEs (LLyα > 0.2L*) at z ≈ 2 obtained from resolved Lyα profiles, and arguing for their redshift-invariance, we show that: (i) quasars and LAEs together reproduce the relatively flat emissivity at z ≈ 2–6, which is non-trivial given the strong evolution in both the star formation density and quasar number density at these epochs and (ii) LAEs produce late and rapid reionization between z ≈ 6−9 under plausible assumptions. Within this framework, the >10 × rise in the UV population-averaged fesc between z ≈ 3–7 naturally arises due to the same phenomena that drive the growing LAE fraction with redshift. Generally, a LAE dominated emissivity yields a peak in the distribution of the ionizing budget with UV luminosity as reported in latest simulations. Using our adopted parameters ($f_{\rm {esc}}=50{{\ \rm per\ cent}}$, ξion = 1025.9 Hz erg−1 formore »half the bright LAEs), a highly ionizing minority of galaxies with MUV < −17 accounts for the entire ionizing budget from star-forming galaxies. Rapid flashes of LyC from such rare galaxies produce a ‘disco’ ionizing background. We conclude proposing tests to further develop our suggested Lyα-anchored formalism.

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    The ionizing photon escape fraction [Lyman continuum (LyC) fesc] of star-forming galaxies is the single greatest unknown in the reionization budget. Stochastic sightline effects prohibit the direct separation of LyC leakers from non-leakers at significant redshifts. Here we circumvent this uncertainty by inferring fesc using resolved (R > 4000) Lyman α (Lyα) profiles from the X-SHOOTER Lyα survey at z = 2 (XLS-z2). With empirically motivated criteria, we use Lyα profiles to select leakers ($f_{\mathrm{ esc}} > 20{{\ \rm per\ cent}}$) and non-leakers ($f_{\mathrm{ esc}} < 5{{\ \rm per\ cent}}$) from a representative sample of >0.2L* Lyman α emitters (LAEs). We use median stacked spectra of these subsets over λrest ≈ 1000–8000 Å to investigate the conditions for LyC fesc. Our stacks show similar mass, metallicity, MUV, and βUV. We find the following differences between leakers versus non-leakers: (i) strong nebular C iv and He ii emission versus non-detections; (ii) [O iii]/[O ii] ≈ 8.5 versus ≈3; (iii) Hα/Hβ indicating no dust versus E(B − V) ≈ 0.3; (iv) Mg ii emission close to the systemic velocity versus redshifted, optically thick Mg ii; and (v) Lyα fesc of ${\approx} 50{{\ \rm per\ cent}}$ versus ${\approx} 10{{\ \rm per\ cent}}$. The extreme equivalent widths (EWs) in leakers ([O iii]+$\mathrm{ H}\beta \approx 1100$ Å rest frame)more »constrain the characteristic time-scale of LyC escape to ≈3–10 Myr bursts when short-lived stars with the hardest ionizing spectra shine. The defining traits of leakers – extremely ionizing stellar populations, low column densities, a dust-free, high-ionization state interstellar medium (ISM) – occur simultaneously in the $f_{\rm esc} > 20{{\ \rm per\ cent}}$ stack, suggesting they are causally connected, and motivating why indicators like [O iii]/[O ii] may suffice to constrain fesc at z > 6 with the James Webb Space Telescope (JWST). The leakers comprise half of our sample, have a median LyC$f_{\rm esc} \approx 50{{\ \rm per\ cent}}$ (conservative range: $20\!-\!55{{\ \rm per\ cent}}$), and an ionizing production efficiency $\log ({\xi _{\rm {ion}}/\rm {Hz\ erg^{-1}}})\approx 25.9$ (conservative range: 25.7–25.9). These results show LAEs – the type of galaxies rare at z ≈ 2, but that become the norm at higher redshift – are highly efficient ionizers, with extreme ξion and prolific fesc occurring in sync.

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  5. Abstract

    We use new Hubble Space Telescope (HST) images of nine Green Pea galaxies (GPGs) to study their resolved structure and color. The choice of filters, F555W and F850LP, together with the redshift of the galaxies (z∼ 0.25), minimizes the contribution of the nebular [Oiii] and Hαemission lines to the broadband images. While these galaxies are typically very blue in color, our analysis reveals that it is only the dominant stellar clusters that are blue. Each GPG does clearly show the presence of at least one bright and compact star-forming region, but these are invariably superimposed on a more extended and lower surface brightness emission. Moreover, the colors of the star-forming regions are on average bluer than those of the diffuse emission, reaching up to 0.6 magnitudes bluer. Assuming that the diffuse and compact components have constant and single-burst star formation histories, respectively, the observed colors imply that the diffuse components (possibly the host galaxy of the star formation episode) have, on average, old stellar ages (>1 Gyr), while the star clusters are younger than 500 Myr. While a redder stellar component is perhaps the most plausible explanation for these results, the limitations of our current data set lead usmore »to examine possible alternative mechanisms, particularly recombination emission processes, which are unusually prominent in systems with such strong line emission. With the available data, however, it is not possible to distinguish between these two interpretations. A substantial presence of old stars would indicate that the mechanisms allowing large escape fractions in these local galaxies may be different from those at play during the reionization epoch.

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  6. Abstract

    Far-ultraviolet (FUV; ∼1200–2000 Å) spectra are fundamental to our understanding of star-forming galaxies, providing a unique window on massive stellar populations, chemical evolution, feedback processes, and reionization. The launch of the James Webb Space Telescope will soon usher in a new era, pushing the UV spectroscopic frontier to higher redshifts than ever before; however, its success hinges on a comprehensive understanding of the massive star populations and gas conditions that power the observed UV spectral features. This requires a level of detail that is only possible with a combination of ample wavelength coverage, signal-to-noise, spectral-resolution, and sample diversity that has not yet been achieved by any FUV spectral database. We present the Cosmic Origins Spectrograph Legacy Spectroscopic Survey (CLASSY) treasury and its first high-level science product, the CLASSY atlas. CLASSY builds on the Hubble Space Telescope (HST) archive to construct the first high-quality (S/N1500 Å≳ 5/resel), high-resolution (R∼ 15,000) FUV spectral database of 45 nearby (0.002 <z< 0.182) star-forming galaxies. The CLASSY atlas, available to the public via the CLASSY website, is the result of optimally extracting and coadding 170 archival+new spectra from 312 orbits of HST observations. The CLASSY sample covers a broad range of properties including stellarmore »mass (6.2 < logM(M) < 10.1), star formation rate (−2.0 < log SFR (Myr−1) < +1.6), direct gas-phase metallicity (7.0 < 12+log(O/H) < 8.8), ionization (0.5 < O32< 38.0), reddening (0.02 <E(BV) < 0.67), and nebular density (10 <ne(cm−3) < 1120). CLASSY is biased to UV-bright star-forming galaxies, resulting in a sample that is consistent with thez∼ 0 mass–metallicity relationship, but is offset to higher star formation rates by roughly 2 dex, similar toz≳ 2 galaxies. This unique set of properties makes the CLASSY atlas the benchmark training set for star-forming galaxies across cosmic time.

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