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Abstract This paper describes the cryogenic and purification systems of the ICARUS T600 detector in its present implementation at the Fermi National Laboratory, Illinois, U.S.A. The ICARUS T600 detector is made of four large Time Projection Chambers, installed in two separate containers of about 275 m³each. The detector uses liquid argon both as target and as active medium. For the correct operation of the detector, the liquid argon must be kept in very stable thermal conditions and the contamination of electronegative impurities must be consistently kept at the level of small fractions of parts per billion. The detector was previously operated in Italy, at the INFN Gran Sasso Underground Laboratory (LNGS), in a three-year run on the CERN to LNGS Long Baseline Neutrino Beam. For its operation on the Booster and NuMI neutrino beams at Fermilab, for the search of sterile neutrinos and measurements of neutrino-argon cross sections, the detector was moved from Gran Sasso to CERN for the upgrades required for operation at shallow depth with high intensity neutrino beams. The liquid argon containers, the thermal insulation and all the cryogenic equipment have been completely re-designed and rebuilt, following the schemes of the previous installation in Gran Sasso. The detector and all the equipment have been transported to Fermilab, where they have been installed, tested and recently put into operation. The work described in this paper has been conducted as a joint responsibility of CERN and Fermilab with the supervision provided by the ICARUS Collaboration. Design, installation, testing, commissioning and operation are the result of a common effort of CERN, Fermilab and INFN groups. 

The short-baseline near detector (SBND), the near detector in the short-baseline neutrino program at Fermi National Accelerator Laboratory, is located just 110 m from the booster neutrino beam target. Thanks to this close proximity, relative to its $4\mathrm{m}\times 4\mathrm{m}$front face, neutrinos enter SBND over a range of angles from 0° to approximately 1.6°, enabling the detector to sample variations in the neutrino flux as a function of the angle—a technique known as precision reaction-independent spectrum measurement (PRISM), referred to here as SBND-PRISM. In this paper, we show how muon- and electron-neutrino fluxes vary as a function of the neutrino beam axis angle and how this can be exploited to expand the physics potential of SBND. We make use of a model that predicts an angle-dependent electron-neutrino excess signal to illustrate this effect, such as ${\nu }_{\mu }\to {\nu }_e$oscillations. We present how SBND-PRISM provides a method to add robustness against uncertainties in cross-section modeling and, more generally, uncertainties that do not depend on the spatial position of neutrino interaction inside the detector. The fluxes, along with their associated covariance matrices, are made publicly available with this publication. 

Abstract The ICARUS liquid argon TPC detector is taking data on the Booster (BNB) and Main Injector (NuMI) Neutrino beam lines at Fermilab with a trigger system based on the scintillation light produced by charged particles in coincidence with the proton beam extraction from the accelerators. The architecture and the deployment of the trigger system in the first two runs for physics are presented, as well as the triggered event rates. The event recognition efficiency has been evaluated as a function of the deposited energy and the position of cosmic muons stopping inside the detector. 

We present a search for long-lived particles (LLPs), produced in kaon decays, that decay to two muons inside the ICARUS neutrino detector. This channel would be a signal of hidden sector models that can address outstanding issues in particle physics such as the strong CP problem and the microphysical origin of dark matter. The search is performed with data collected in the Neutrinos at the Main Injector (NuMI) beam at Fermilab corresponding to $2.41\times {10}^{20}$protons-on-target. No new physics signal is observed, and we set world leading limits on heavy QCD axions, as well as for the Higgs portal scalar among dedicated searches. Limits are also presented in a model-independent way applicable to any new physics model predicting the process $K\to \pi +S(\to \mu \mu )$, for a LLP $S$. This result is the first search for new physics performed with the ICARUS detector at Fermilab. It paves the way for the future program of LLP searches at ICARUS. Published by the American Physical Society2025 

Abstract The ICARUS liquid argon time projection chamber (LArTPC) neutrino detector has been taking physics data since 2022 as part of the Short-Baseline Neutrino (SBN) Program. This paper details the equalization of the response to charge in the ICARUS time projection chamber (TPC), as well as data-driven tuning of the simulation of ionization charge signals and electronics noise. The equalization procedure removes non-uniformities in the ICARUS TPC response to charge in space and time. This work leverages the copious number of cosmic ray muons available to ICARUS at the surface. The ionization signal shape simulation applies a novel procedure that tunes the simulation to match what is measured in data. The end result of the equalization procedure and simulation tuning allows for a comparison of charge measurements in ICARUS between Monte Carlo simulation and data, showing good performance with minimal residual bias between the two. 

Abstract This paper reports on a measurement of electron-ion recombination in liquid argon in the ICARUS liquid argon time projection chamber (LArTPC). A clear dependence of recombination on the angle of the ionizing particle track relative to the drift electric field is observed. An ellipsoid modified box (EMB) model of recombination describes the data across all measured angles. These measurements are used for the calorimetric energy scale calibration of the ICARUS TPC, which is also presented. The impact of the EMB model is studied on calorimetric particle identification, as well as muon and proton energy measurements. Accounting for the angular dependence in EMB recombination improves the accuracy and precision of these measurements. 

We present the measurement of ${\pi }^{+}$-argon inelastic cross sections using the ProtoDUNE single-phase liquid argon time projection chamber in the incident ${\pi }^{+}$kinetic energy range of 500–800 MeV in multiple exclusive channels (absorption, charge exchange, and the remaining inelastic interactions). The results of this analysis are important inputs to simulations of liquid argon neutrino experiments such as the Deep Underground Neutrino Experiment and the Short Baseline Neutrino program at Fermi National Accelerator Laboratory. They will be employed to improve the modeling of final state interactions within neutrino event generators used by these experiments, as well as the modeling of ${\pi }^{+}$-argon secondary interactions within the liquid argon. This is the first measurement of ${\pi }^{+}$-argon absorption at this kinetic energy range as well as the first ever measurement of ${\pi }^{+}$-argon charge exchange. 

The 2x2 Demonstrator, a prototype for the Deep Underground Neutrino Experiment (DUNE) liquid argon (LAr) Near Detector, was exposed to the Neutrinos from the Main Injector (NuMI) neutrino beam at Fermi National Accelerator Laboratory (Fermilab). This detector is a prototype of a new modular design for a liquid argon time-projection chamber (LArTPC), comprising a two-by-two array of four modules, each further segmented into two optically isolated LArTPCs. The 2x2 Demonstrator features a number of pioneering technologies, including a low-profile resistive field shell to establish drift fields, native 3D ionization pixelated imaging, and a high-coverage dielectric light readout system. The 2.4-tonne active mass detector is flanked upstream and downstream by supplemental solid-scintillator tracking planes, repurposed from the MINERvA experiment, which track ionizing particles exiting the argon volume. The antineutrino beam data collected by the detector over a 4.5 day period in 2024 include over 30,000 neutrino interactions in the LAr active volume—the first neutrino interactions reported by a DUNE detector prototype. During its physics-quality run, the 2x2 Demonstrator operated at a nominal drift field of 500 V/cm and maintained good LAr purity, with a stable electron lifetime of approximately 1.25 ms. This paper describes the detector and supporting systems, summarizes the installation and commissioning, and presents the initial validation of collected NuMI beam and off-beam self-triggers. In addition, it highlights observed interactions in the detector volume, including candidate muon antineutrino events. 

The Deep Underground Neutrino Experiment (DUNE) is a next-generation neutrino experiment with a rich physics program that includes searches for the hypothetical phenomenon of proton decay. Utilizing liquid-argon time-projection chamber technology, DUNE is expected to achieve world-leading sensitivity in the proton decay channels that involve charged kaons in their final states. The first DUNE demonstrator, ProtoDUNE Single-Phase, was a 0.77 kt detector that operated from 2018 to 2020 at the CERN Neutrino Platform, exposed to a mixed hadron and electron test-beam with momenta ranging from 0.3 to $7\mathrm{GeV}/\mathrm{c}$. We present a selection of low-energy kaons among the secondary particles produced in hadronic reactions, using data from the 6 and $7\mathrm{GeV}/\mathrm{c}$beam runs. The selection efficiency is 1% and the sample purity 92%. The initial energies of the selected kaon candidates encompass the expected energy range of kaons originating from proton decay events in DUNE (below $\sim 200\mathrm{MeV}$). In addition, we demonstrate the capability of this detector technology to discriminate between kaons and other particles such as protons and muons, and provide a comprehensive description of their energy loss in liquid argon, which shows good agreement with the simulation. These results pave the way for future proton decay searches at DUNE. 

Abstract Liquid argon time projection chambers (LArTPCs) rely on highly pure argon to ensure that ionization electrons produced by charged particles reach readout arrays. ProtoDUNE Single-Phase (ProtoDUNE-SP) was an approximately 700-ton liquid argon detector intended to prototype the Deep Underground Neutrino Experiment (DUNE) Far Detector Horizontal Drift module. It contains two drift volumes bisected by the cathode plane assembly, which is biased to create an almost uniform electric field in both volumes. The DUNE Far Detector modules must have robust cryogenic systems capable of filtering argon and supplying the TPC with clean liquid. This paper will explore comparisons of the argon purity measured by the purity monitors with those measured using muons in the TPC from October 2018 to November 2018. A new method is introduced to measure the liquid argon purity in the TPC using muons crossing both drift volumes of ProtoDUNE-SP. For extended periods on the timescale of weeks, the drift electron lifetime was measured to be above 30 ms using both systems. A particular focus will be placed on the measured purity of argon as a function of position in the detector.